Elinogrel potassium
Elinogrel (PRT060128) potassium is a reversible, competitive and orally active P2Y12 antagonist. Elinogrel potassium inhibits thrombosis.
For research use only. We do not sell to patients.
- CAS No.: 936501-01-8
- Formula: C20H15ClFKN5O5S2
- Molecular Weight:563.04
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All P2Y Receptor Isoforms
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Biological Activity
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P2Y12 Receptor |
Elinogrel (1 mg/kg; i.v.) blocks residual thrombotic activity observed in clopidogrel (HY-15283)-treated mice (50 mg/kg p.o., 3 days) in a FeCl3 (HY-Y0266)-induced vascular injury model[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:C57BL/6J mice [2]
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Dosage:60 mg/kg
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Administration:P.o.; daily for 3 days
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Result:Inhibited thrombosis in mouse.
Chemical Information
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CAS No. 936501-01-8
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Molecular Weight 563.04
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Formula C20H15ClFKN5O5S2
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SMILES
O=S(C1=CC=C(Cl)S1)(NC(NC2=CC=C(N3C(NC4=C(C=C(F)C(NC)=C4)C3=O)=O)C=C2)=O)=O.[K]
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Synonyms
PRT060128 potassium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Ueno M, et al. Elinogrel: pharmacological principles, preclinical and early phase clinical testing. Future Cardiol. 2010 Jul;6(4):445-53. [Content Brief]
[2]. Haberstock-Debic H, et al. A clopidogrel-insensitive inducible pool of P2Y12 receptors contributes to thrombus formation: inhibition by elinogrel, a direct-acting, reversible P2Y12 antagonist. J Pharmacol Exp Ther. 2011 Oct;339(1):54-61. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Elinogrel potassium Related Classifications
HY-14486 Related Classifications
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