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Cat. No.: HY-100423AR

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Eltanexor Z-isomer (Standard)

Name: Eltanexor Z-isomer (Standard)
Brand: MedChemExpress
SKU: HY-100423AR
Availability: PreOrder

(Synonyms: KPT-8602 (Z-isomer) (Standard))

Eltanexor Z-isomer (Standard) is the analytical standard of Eltanexor Z-isomer (HY-100423A). This product is intended for research and analytical applications. 0

For research use only. We do not sell to patients.

CAS No.: 1642300-78-4
Formula: C₁₇H₁₀F₆N₆O
Molecular Weight:428.29

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Eltanexor Z-isomer (Standard) Chemical Structure

CAS No.: 1642300-78-4

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Product Information

Information

Eltanexor Z-isomer (Standard) is the analytical standard of Eltanexor Z-isomer (HY-100423A). This product is intended for research and analytical applications. 0

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 1642300-78-4
Molecular Weight 428.29
Formula C₁₇H₁₀F₆N₆O
SMILES

O=C(N)/C(C1=CN=CN=C1)=C\N2N=C(C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)N=C2
Synonyms

KPT-8602 (Z-isomer) (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Vercruysse T et al. The second-generation exportin-1 inhibitor KPT-8602 demonstrates potent activity against acute lymphoblastic leukemia. Clin Cancer Res. 2016 Oct 25. [Content Brief]

[2]. Hing ZA et al. Next-generation XPO1 inhibitor shows improved efficacy and in vivo tolerability in hematological malignancies. Leukemia. 2016 Jun 21. [Content Brief]

[3]. Etchin J et al. KPT-8602, a second-generation inhibitor of XPO1-mediated nuclear export, is well tolerated and highly active against AML blasts and leukemia-initiating cells. Leukemia. 2016 Jun 24. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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