1. Membrane Transporter/Ion Channel
  2. CRM1

KPT-8602 Z-isomer (Synonyms: Eltanexor Z-isomer)

Cat. No.: HY-100423A Purity: 95.80%
Handling Instructions

KPT-8602 Z-isomer is the less active isomer of KPT-8602.

For research use only. We do not sell to patients.

KPT-8602 Z-isomer Chemical Structure

KPT-8602 Z-isomer Chemical Structure

CAS No. : 1642300-78-4

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 328 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
1 mg USD 168 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
5 mg USD 348 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
10 mg USD 468 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
50 mg USD 1380 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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Customer Review

  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

KPT-8602 Z-isomer is the less active isomer of KPT-8602. KPT-8602 is a potent CRM1 inhibitor. IC50: In Vitro: KPT 8602 Z-isomer exhibits different inhibitory effects on Z138, MM15, 3T3 cell lines, with IC50s of 100 nM-50 μM, < 100 nM, > 30 μM, respectively[1]. In Vivo:

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3349 mL 11.6743 mL 23.3487 mL
5 mM 0.4670 mL 2.3349 mL 4.6697 mL
10 mM 0.2335 mL 1.1674 mL 2.3349 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

428.29

Formula

C₁₇H₁₀F₆N₆O

CAS No.

1642300-78-4

SMILES

O=C(N)/C(C1=CN=CN=C1)=C\N2N=C(C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)N=C2

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
KPT-8602 Z-isomer
Cat. No.:
HY-100423A
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KPT-8602 Z-isomer

Cat. No.: HY-100423A