Erinacine P
Based on 1 publication(s) in Google Scholar
Erinacine P is a cyathane-type diterpenoid antibacterial agent. Erinacine P is isolated from the biosynthesis of mycelia and submerged cultures of Hericium erinaceum. Erinacine P serves as a precursor for the production of important active components such as Erinacine C, A and B. Erinacine P exhibits significant antibacterial activity against Aliivibrio fischeri.
For research use only. We do not sell to patients.
- Purity : 98.80%
- CAS No.: 291532-17-7
- Formula: C27H40O8
- Molecular Weight:492.60
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Erinacine P
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Biological Activity
Description
In Vitro
Erinacine P (ca. 120 mg/L; 11 days after inoculation) accumulates in Hericium erinaceum YB4-6237 cultures, and 1633.3 mg is isolated from 3 liters of fermentation broth[1].
Erinacine P is isolated in 155 mg yield from Hericium erinaceum YB4-6237 mycelial cultures, and is structurally characterized as a novel cyathane-xyloside[2].
Erinacine P (1-9 days) reaches a maximum concentration of ~184 mg/L at 3 days of incubation in submerged cultures of Hericium erinaceus (strain FU70034) grown in medium 7, after which its concentration declines[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 291532-17-7
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Appearance Solid
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Molecular Weight 492.60
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Formula C27H40O8
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Color White to off-white
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SMILES
C[C@]12C([C@]3([H])[C@]([C@H](C=C([C@@H](C3)OC(C)=O)C=O)O[C@H]4[C@@H]([C@H]([C@@H](CO4)O)O)O)(CC1)C)=C(CC2)C(C)C
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (1)
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Journal Impact Factor
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Most Recent
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Molecules
Polysorbate 80 Differentially Impacts Erinacine Production Profiles in Submerged Cultures of Hericium. [Abstract]2025 Jun 30;30(13):2823. PMID: 40649339
Protocols
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
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Bacterial live/dead nucleic-acid viability staining
The LIVE/DEAD bacterial viability staining method is based on differential permeability of nucleic-acid-binding fluorescent dyes, most commonly SYTO 9 and propidium iodide (PI), which enables discrimination of bacterial populations with intact versus compromised cytoplasmic membranes. SYTO 9 penetrates both intact and damaged bacterial membranes and binds nucleic acids to produce green fluorescence, whereas propidium iodide penetrates only cells with compromised membranes and fluoresces red while also reducing SYTO 9 signal through competitive binding and fluorescence interactions. The resulting fluorescence pattern is interpreted as a proxy for membrane integrity, which is widely used as an indicator of bacterial viability in microscopy, flow cytometry, and spectroscopic platforms. However, mechanistic studies show that SYTO 9 and PI interactions involve displacement and fluorescence resonance energy transfer effects, which can influence signal interpretation depending on dye ratios a
Purity & Documentation
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Data Sheet (278 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Erinacine P Related Classifications
HY-N11019 Related Classifications
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