FAK-IN-14
Based on 1 Customer Validation
FAK-IN-14 (compound 8d) is a focal adhesion kinase(FAK) inhibitor with an IC50 value of 0.2438 nM. FAK-IN-14 induces U87-MG cell early apoptosis and arrest the cell at the G2/M phase.
For research use only. We do not sell to patients.
- Purity: 98.23%
- CAS No.: 2766666-22-0
- Formula: C21H24BrN7OS
- Molecular Weight:502.43
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Bioactive Compound Library Max
HY-L181
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Bioactive Compound Library
HY-L001
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Kinase Inhibitor Library
HY-L009
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Protein Tyrosine Kinase Compound Library
HY-L016
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Anti-Cancer Compound Library
HY-L025
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Cytoskeleton Compound Library
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Anti-Pancreatic Cancer Compound Library
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Anti-Pulmonary Fibrosis Compound Library
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MCE Bioactive Compound Library
HY-L001V
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Protein Kinase Compound Library
HY-L196
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High-Throughput Bioactive Compound Library
HY-L205
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Posttranslational Modification Library
HY-L226
Biological Activity
Chemical Information
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CAS No. 2766666-22-0
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Appearance Solid
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Molecular Weight 502.43
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Formula C21H24BrN7OS
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Color White to off-white
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SMILES
CN(CC1)CCN1C(C=C2)=CC=C2NC3=NC=C(Br)C(NC4=C(C(NC)=O)SC=C4)=N3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 25 mg/mL (49.76 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 1.9903 mL | 9.9516 mL | 19.9033 mL | 49.7582 mL |
| 5 mM | 0.3981 mL | 1.9903 mL | 3.9807 mL | 9.9516 mL | |
| 10 mM | 0.1990 mL | 0.9952 mL | 1.9903 mL | 4.9758 mL | |
| 15 mM | 0.1327 mL | 0.6634 mL | 1.3269 mL | 3.3172 mL | |
| 20 mM | 0.0995 mL | 0.4976 mL | 0.9952 mL | 2.4879 mL | |
| 25 mM | 0.0796 mL | 0.3981 mL | 0.7961 mL | 1.9903 mL | |
| 30 mM | 0.0663 mL | 0.3317 mL | 0.6634 mL | 1.6586 mL | |
| 40 mM | 0.0498 mL | 0.2488 mL | 0.4976 mL | 1.2440 mL |
FAK-IN-14 Related Classifications
HY-155439 Related Classifications
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