Fesomersen
Fesomersen is an antisense oligonucleotide designed to inhibit the production of Factor XI.
For research use only. We do not sell to patients.
- CAS No.: 2380135-03-3
- Formula: C296H434N82O156P20S13
- Molecular Weight:8673.49
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 2380135-03-3
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Molecular Weight 8673.49
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Formula C296H434N82O156P20S13
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SMILES
[Fesomersen]
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Synonyms
ION-957943 free acid; BAY-3563450; IONIS-FXI-LRx
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Gómez-Outes A, Suárez-Gea ML, Pérez-Cabeza AI, García-Pinilla JM. Pharmacotherapy for stroke prevention in nonvalvular atrial fibrillation: current strategies and future directions. Expert Opin Pharmacother. 2022;23(17):1941-1955. [Content Brief]
[2]. Fredenburgh JC, Weitz JI. News at XI: Moving Beyond Factor Xa Inhibitors [published online ahead of print, 2023 Apr 26]. J Thromb Haemost. 2023;S1538-7836(23)00343-4. doi:10.1016/j.jtha.2023.04.021 [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)