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  2. FM-red

FM-red (Synonyms: PSH-red)

Cat. No.: HY-D1260
Handling Instructions

FM-red (PSH-red) is a red-emitting and environment-sensitive probe for selectively detecting and labeling protein thiols. FM-red can be used to image protein sulfhydryl groups in live cells and in vivo. FM-red also could be used to measure of the redox states of thioredoxin (Trx).

For research use only. We do not sell to patients.

FM-red Chemical Structure

FM-red Chemical Structure

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Description

FM-red (PSH-red) is a red-emitting and environment-sensitive probe for selectively detecting and labeling protein thiols. FM-red can be used to image protein sulfhydryl groups in live cells and in vivo. FM-red also could be used to measure of the redox states of thioredoxin (Trx)[1].

In Vitro

FM-red (10 μM; 30 min) is suitable for imaging protein thiols in HeLa cells[1].
FM-red (20 μM; 48 h) has no significant cytotoxicity in HeLa cells[1].
FM-red possesses a long emission wavelength (~655 nm) and fast response (~10 min) by binding to protein thiols[1].
FM-red exhibits time- and concentration-dependent fluorescence response to bovine serum albumin (BSA)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

FM-red (10 μM; 30 min) could be used to image protein thiols in zebrafishes[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

788.29

Formula

C₄₁H₄₆ClN₅O₉

SMILES

CN(C1=CC=C(C2=[O+]C3=C(C=CC(N(CC)CC)=C3)C(C4=C(C=CC=C4)C(N5CCC(CC5)NC(CCCN6C(C=CC6=O)=O)=O)=O)=C2)C=C1)C.O=Cl(=O)([O-])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

FM-redPSH-redOthersred-emittingenvironmentsensitiveproteinthiolssulfhydrylredoxstatesthioredoxinTrxInhibitorinhibitorinhibit

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FM-red
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HY-D1260
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