CEF3
CEF3 (SIIPSGPLK) corresponds to aa 13-21 of the influenza A virus M1 protein. The matrix (M1) protein of influenza A virus is a multifunctional protein that plays essential structural and functional roles in the virus life cycle.
For research use only. We do not sell to patients.
- CAS No.: 199727-62-3
- Formula: C42H74N10O12
- Molecular Weight:911.10
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
The matrix (M1) protein of influenza A virus is a multifunctional protein that plays essential structural and functional roles in the virus life cycle. It drives virus budding and is the major protein component of the virion, where it forms an intermediate layer between the viral envelope and integral membrane proteins and the genomic ribonucleoproteins (RNPs). It also helps to control the intracellular trafficking of RNPs. These roles are mediated primarily via protein-protein interactions with viral and possibly cellular proteins[1]. The influenza virus M1 is required to induce vRNP nuclear export but that cellular phosphorylation is an additional factor. The influenza virus M1 protein is fundamental to a late event in the virus life cycle-the transfer of vRNPs from the nucleus to the cytosol[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 199727-62-3
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Molecular Weight 911.10
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Formula C42H74N10O12
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Sequence
Ser-Ile-Ile-Pro-Ser-Gly-Pro-Leu-Lys
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Sequence Shortening
SIIPSGPLK
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Structure Classification
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Initial Source
yeast Saccharomyces cerevisiae
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Noton SL, et al. Identification of the domains of the influenza A virus M1 matrix protein required for NP binding, oligomerization and incorporation into virions. J Gen Virol. 2007 Aug;88(Pt 8):2280-90. [Content Brief]
[2]. Bui M, et al. Role of the influenza virus M1 protein in nuclear export of viral ribonucleoproteins. J Virol. 2000 Feb;74(4):1781-6. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CEF3 Related Classifications
HY-P0289 Related Classifications
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