VHC-7
VHC-7 is a potent and selective adenylyl cyclase type 8 (AC8) agonist, with an EC50 value of 105.2 nM. VHC-7 increases cyclic adenosine monophosphate (cAMP) levels. VHC-7 can be used for the study of central nervous system disorders and heart diseases.
For research use only. We do not sell to patients.
- CAS No.: 14750-21-1
- Formula: C18H15Cl2NO3
- Molecular Weight:364.22
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | EC50 |
0.1052 μM
Compound: VHC-7
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Agonist activity at recombinant human AC8 expressed in human HEK293 cells assessed as fold increase in cAMP level by LANCE Ultra cAMP Detection kit method
Agonist activity at recombinant human AC8 expressed in human HEK293 cells assessed as fold increase in cAMP level by LANCE Ultra cAMP Detection kit method
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[PMID: 31776060] |
Chemical Information
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CAS No. 14750-21-1
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Molecular Weight 364.22
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Formula C18H15Cl2NO3
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SMILES
O=C(C1(CC2=CC=C(Cl)C=C2Cl)C(NC3=C1C=CC=C3)=O)OCC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
VHC-7 Related Classifications
HY-130629 Related Classifications
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