BCAT-IN-4
Based on 1 Customer Validation
BCAT-IN-4 (Compound 1) is a BCAT inhibitor. BCAT-IN-4 exhibits a moderate ability to inhibit hBCATc with IC50 value of 2.35 μM. BCAT-IN-4 can be used for the research of neurodegenerative diseases.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 98.57%
- No. CAS: 406190-85-0
- Fòrmula: C19H14N2O4S
- Peso molecular:366.39
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Almacenamiento:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Protocolo
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
Descripciòn
IC50 & Target
IC50: 2.35 μM (hBCATc)[1].
Chemical Information
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No. CAS 406190-85-0
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Appearance Solid
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Peso molecular 366.39
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Fòrmula C19H14N2O4S
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Color White to off-white
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SMILES
O=C(C1=CC2=C(OC3=C2C=CC=C3)C=C1)NNS(=O)(C4=CC=CC=C4)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
In Vitro:
DMSO : ≥ 125 mg/mL (341.17 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Protocolo
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Pureza y Documentación
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Ficha de datos (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.7293 mL | 13.6467 mL | 27.2933 mL | 68.2333 mL |
| 5 mM | 0.5459 mL | 2.7293 mL | 5.4587 mL | 13.6467 mL | |
| 10 mM | 0.2729 mL | 1.3647 mL | 2.7293 mL | 6.8233 mL | |
| 15 mM | 0.1820 mL | 0.9098 mL | 1.8196 mL | 4.5489 mL | |
| 20 mM | 0.1365 mL | 0.6823 mL | 1.3647 mL | 3.4117 mL | |
| 25 mM | 0.1092 mL | 0.5459 mL | 1.0917 mL | 2.7293 mL | |
| 30 mM | 0.0910 mL | 0.4549 mL | 0.9098 mL | 2.2744 mL | |
| 40 mM | 0.0682 mL | 0.3412 mL | 0.6823 mL | 1.7058 mL | |
| 50 mM | 0.0546 mL | 0.2729 mL | 0.5459 mL | 1.3647 mL | |
| 60 mM | 0.0455 mL | 0.2274 mL | 0.4549 mL | 1.1372 mL | |
| 80 mM | 0.0341 mL | 0.1706 mL | 0.3412 mL | 0.8529 mL | |
| 100 mM | 0.0273 mL | 0.1365 mL | 0.2729 mL | 0.6823 mL |
BCAT-IN-4 Related Classifications
HY-153878 Related Classifications
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