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Referencia número: HY-137979

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Flunitrazolam

Name: Flunitrazolam
Brand: MedChemExpress
SKU: HY-137979
Price: 215.00 USD
Availability: PreOrder

(Synonyms: FNTZ)

Flunitrazolam (FNTZ) is an orally active triazolobenzodiazepine designer benzodiazepine compound and a positive allosteric modulator of the GABA_A receptor. Flunitrazolam undergoes biometabolic transformation, and 7-amino-flunitrazolam and 7-acetamido-flunitrazolam are its main detectable metabolites in urine. Flunitrazolam can be used in research related to GABA-mediated diseases, such as neurological disorders.

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS: 2243815-18-9
Fòrmula: C₁₇H₁₂FN₅O₂
Peso molecular:337.31

Almacenamiento:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

Flunitrazolam Chemical Structure

No. CAS: 2243815-18-9

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- In Vitro
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
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Actividad biológica

Descripciòn

In Vitro

Flunitrazolam (compound 36) acts as a positive allosteric modulator of α1β2γ2 GABA_A receptors in CHO cells, and its activity depends on the classical BZD α⁺/γ2^- binding pocket.^[1]
Flunitrazolam (FNTZ) undergoes biotransformation, and 7-amino-FNTZ and 7-acetamido-FNTZ are its main detectable metabolites in urine; moreover, in human liver microsomes, 7-amino-FNTZ is the only metabolite of flunitrazolam produced under the study conditions^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 2243815-18-9
Appearance Solid
Peso molecular 337.31
Fòrmula C₁₇H₁₂FN₅O₂
Color Light yellow to yellow
SMILES

O=[N+](C1=CC=C(N2C(CN=C3C4=CC=CC=C4F)=NN=C2C)C3=C1)[O-]
Synonyms

FNTZ
Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (294 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Norman C, et al. In vitro γ-aminobutyric acid A (GABA) receptor activity and binding interactions at the α/γ interface of 53 prescription and designer benzodiazepines. Communications chemistry. 2026 Apr 07;9(1):155.

[2]. Ameline A, et al. Detection of the designer benzodiazepine flunitrazolam in urine and preliminary data on its metabolism. Drug testing and analysis. 2019 Feb;11(2):223-229.

[3]. Cornett EM, et al. New benzodiazepines for sedation. Best Practice & Research Clinical Anaesthesiology. 2018 Jun 1;32(2):149-64.

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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