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Referencia número: HY-120581

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ML388

ML388 is a potent and selective hydroxyprostaglandin dehydrogenase (HPGD) inhibitor with an IC₅₀ of 34 nM. ML388 induces PGE2 production in A549 cells and LNCaP prostate cancer cells.

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No. CAS: 1537192-31-6
Fòrmula: C₂₀H₂₄N₄
Peso molecular:320.43

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

ML388 Chemical Structure

No. CAS: 1537192-31-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- IC₅₀ & Target
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
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Actividad biológica

Descripciòn

ML388 is a potent and selective hydroxyprostaglandin dehydrogenase (HPGD) inhibitor with an IC₅₀ of 34 nM. ML388 induces PGE2 production in A549 cells and LNCaP prostate cancer cells^[1].

IC₅₀ & Target

IC50: 34 nM (hydroxyprostaglandin dehydrogenase (HPGD))^[1]

Chemical Information

No. CAS 1537192-31-6
Peso molecular 320.43
Fòrmula C₂₀H₂₄N₄
SMILES

CC1=CC=C(C=C1)N2C(C)=C(C=C2C)C3=NN=C4N3CCCCC4
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Damien Y. Duveau, et al. Discovery of two small molecule inhibitors, ML387 and ML388, of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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