MRT2000769
MRT2000769 is a Kir7.1 inhibitor with an IC50 of 2 μM. MRT2000769 induces sustained contractions in the uterine muscle of pregnant mice. MRT2000769 is applicable for the research of postpartum hemorrhage.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 1214573-32-6
- Fòrmula: C21H26FNO4
- Peso molecular:375.44
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
- Protocolo
- Pureza y Documentación
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Help & FAQs
Actividad biológica
Descripciòn
IC50 & Target
[1]|
Kir7.1 2 μM (IC50) |
In Vitro
MRT2000769 (1.1-3.5 μM) potently inhibits recombinant Kir7.1 channels expressed in Chinese hamster ovary cells, with an IC50 of 2 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 1214573-32-6
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Peso molecular 375.44
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Fòrmula C21H26FNO4
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SMILES
FC1=CC=CC(OC2CCN(CC2)CC(O)C3=CC(OC)=CC=C3OC)=C1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocolo
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MRT2000769 Related Classifications
HY-122638 Related Classifications
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