WO677
WO677 is a KCNT1 inhibitor that can be used in studies of nervous system disorders associated with KCNT1 function, such as epilepsy.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 3088105-77-2
- Fòrmula: C18H14F6N6O2
- Peso molecular:460.33
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Descripciòn
In Vitro
WO677 (I‑1a) exhibits an IC50 ≤ 250 nM in the FLIPR calcium flux inhibition assay[1].
WO677 can be obtained via trifluoroacetic acid treatment, palladium-catalyzed C-N coupling, titanium-mediated imine formation, and diastereomeric intermediate conversion[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 3088105-77-2
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Peso molecular 460.33
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Fòrmula C18H14F6N6O2
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SMILES
CN1N=C(C(F)(F)F)C=C1C(N[C@H]2COCC3=NN(C4=CC(C(F)(F)F)=NC=C4)C=C32)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)