Tdrd7 - tudor domain containing 7 Gene

Also Known as PCTAIRE2BP; 5730495N10Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 100121

Summary

Predicted to enable mRNA binding activity and protein N-terminus binding activity. Involved in lens fiber cell differentiation; lens morphogenesis in camera-type eye; and spermatogenesis. Acts upstream of or within germ cell development. Located in P granule and chromatoid body. Part of ribonucleoprotein complex. Is expressed in several structures, including central nervous system; olfactory epithelium; retina; and seminiferous tubule. Human ortholog(s) of this gene implicated in cataract 36. Orthologous to human TDRD7 (tudor domain containing 7). [provided by Alliance of Genome Resources, Apr 2022]

Tdrd7 Products (3)

mRNA Protein Name
NM_001290475.1 NP_001277404.1 tudor domain-containing protein 7 isoform 1
NM_001355189.1 NP_001342118.1 tudor domain-containing protein 7 isoform 2
NM_146142.2 NP_666254.1 tudor domain-containing protein 7 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16787967 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within germ cell development IDA
IDA: Inferred from direct assay
17141210 MGI
involved in lens fiber cell differentiation IMP
IMP: Inferred from mutant phenotype
21436445 MGI
involved in lens morphogenesis in camera-type eye IMP
IMP: Inferred from mutant phenotype
21436445 MGI
involved in spermatogenesis IMP
IMP: Inferred from mutant phenotype
21436445 MGI
Cellular Component GO Annotation Evidence References Source
located in P granule IDA
IDA: Inferred from direct assay
17141210 MGI
located in chromatoid body IDA
IDA: Inferred from direct assay
17141210 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
17141210 MGI
part of ribonucleoprotein complex IDA
IDA: Inferred from direct assay
17141210 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tudor domain-containing protein 7

  • PCTAIRE2-binding protein

  • trap

  • tudor repeat associator with PCTAIRE 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14338 TDRD7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22851 Tdrd7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29365 Tdrd7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tdrd7 NCBI NCBI:23424