2. Gene
  3. ARL4C - ADP ribosylation factor like GTPase 4C Gene

ARL4C - ADP ribosylation factor like GTPase 4C Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as LAK; ARL7

Gene ID: 10123 | Gene type: protein coding

About ARL4C

Cytogenetic location: 2q37.1 Genomic coordinates (GRCh38): 2:234,493,041-234,497,081 (from NCBI)

This gene has 2 transcripts (splice variants), 213 orthologues and 30 paralogues. Broad expression in lymph node (RPKM 30.2), spleen (RPKM 30.0) and 20 other tissues.

Summary

ADP-ribosylation factor-like 4C is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL4C is closely similar to ARL4A and ARL4D and each has a nuclear localization signal and an unusually high guanine nucleotide exchange rate. This protein may play a role in Cholesterol transport. [provided by RefSeq, Jul 2008]

ARL4C Products(2)

mRNA Protein Name
NM_001282431.2 NP_001269360.1 ADP-ribosylation factor-like protein 4C isoform 1
NM_005737.3 NP_005728.2 ADP-ribosylation factor-like protein 4C isoform 2

ARL4C Protein Structure

Arf

Arf: ADP-ribosylation factor family (8 - 179)

  • 0
  • 100
  • 192 a.a.
Protein Preferred Names Protein Names

ADP-ribosylation factor-like protein 4C

ADP ribosylation factor-like protein 7

Related Diseases

Diseases Alias
Vulvar Leiomyosarcoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00989 ARL4C Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris ARL4C VGNC VGNC:38113
Felis catus ARL4C VGNC VGNC:80138
Rattus norvegicus ARL4C RGD RGD:1589685
Macaca mulatta ARL4C VGNC VGNC:70018
Bos taurus ARL4C VGNC VGNC:26145
Mus musculus ARL4C MGD MGI:2445172