COMT - catechol-O-methyltransferase Gene

Macaca fascicularis

Gene ID: 102114823 | Gene type: protein coding

About COMT

Primary_assembly 10: 31,997,361-32,025,921 reverse strand.Macaca_fascicularis_6.0:CM021948.1

This gene has 3 transcripts (splice variants), 276 orthologues and 1 paralogue.

mRNA	Protein	Name
XM_045363987.1	XP_045219922.1	catechol O-methyltransferase isoform X1
XM_005567962.3	XP_005568019.1	catechol O-methyltransferase isoform X2
XM_045363988.1	XP_045219923.1	catechol O-methyltransferase isoform X1
XM_015457426.2	XP_015312912.1	catechol O-methyltransferase isoform X2
XM_045363995.1	XP_045219930.1	catechol O-methyltransferase isoform X2
XM_045363984.1	XP_045219919.1	catechol O-methyltransferase isoform X1
XM_045363990.1	XP_045219925.1	catechol O-methyltransferase isoform X1
XM_015457427.2	XP_015312913.1	catechol O-methyltransferase isoform X3
XM_015457423.2	XP_015312909.1	catechol O-methyltransferase isoform X2
XM_045363989.1	XP_045219924.1	catechol O-methyltransferase isoform X1
XM_045363985.1	XP_045219920.1	catechol O-methyltransferase isoform X1
XM_045363992.1	XP_045219927.1	catechol O-methyltransferase isoform X1
XM_045363991.1	XP_045219926.1	catechol O-methyltransferase isoform X1
XM_045363993.1	XP_045219928.1	catechol O-methyltransferase isoform X1
XM_045363986.1	XP_045219921.1	catechol O-methyltransferase isoform X1

YrrM

Protein Preferred Names

Protein Names

catechol O-methyltransferase

Approval

Bioactive Molecules (10)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-B1473A	Serotonin	Inhibitor	99.86%	Unkown
HY-B1473	Serotonin hydrochloride	Inhibitor	99.97%	Unkown
HY-17406	Tolcapone	Inhibitor	99.86%	Yes
HY-14280	Entacapone	Inhibitor	99.97%	Yes
HY-14896	Opicapone	Inhibitor	98.81%	Yes
HY-100562	Flopropione	Inhibitor	99.97%	Unkown
HY-B1473R	Serotonin hydrochloride (Standard)	Inhibitor	99.28%	Unkown
HY-14280R	Entacapone (Standard)	Inhibitor	99.24%	Unkown
HY-17406R	Tolcapone (Standard)	Inhibitor	/	Unkown
HY-14280A	Entacapone sodium salt	Inhibitor	/	Unkown

Clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Phase
HY-N0529	Rosmarinic acid	Inhibitor	99.73%	Phase 3
HY-106405	Nebicapone	Inhibitor	99.89%	Phase 2
HY-106842	Nitecapone	Inhibitor	98.71%	Phase 2
HY-19061	CGP 28014	Inhibitor	/	Phase 2

Pre-clinical Phase

Bioactive Molecules (30)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-B1473AS	Serotonin-d4	Inhibitor	99.60%	Unkown
HY-N0522	(-)-Gallocatechin gallate	Inhibitor	99.97%	Unkown
HY-B1473S	Serotonin-d4 hydrochloride	Inhibitor	99.48%	Unkown
HY-133068	5-Hydroxyferulic acid		99.43%	Unkown
HY-125339	Ro 41-0960	Inhibitor	98.22%	Unkown
HY-100959	3,5-Dinitrocatechol	Inhibitor	99.72%	Unkown
HY-W012264	3-O-Methyldopa monohydrate		99.16%	Unkown
HY-128410	4-Phenyl-7,8-dihydroxycoumarin	Inhibitor	99.35%	Unkown
HY-151388	hMAO-B/MB-COMT-IN-1	Inhibitor	98.04%	Unkown
HY-157719	S-Adenosylhomocysteine sulfoxide	Inhibitor	≥95.0%	Unkown
HY-17406S1	Tolcapone-d4	Inhibitor	99.13%	Unkown
HY-121949	U-0521	Inhibitor	98.67%	Unkown
HY-14280S	Entacapone-d10	Inhibitor	98.6%	Unkown
HY-120325	DHMPA	Inhibitor	/	Unkown
HY-W704878	(Z)-Entacapone-d10-1		/	Unkown
HY-17406S	Tolcapone-d7	Inhibitor	/	Unkown
HY-139089	(Z)-Entacapone	Inhibitor	/	Unkown
HY-100642S1	3-O-Methyltolcapone-d4	Inhibitor	/	Unkown
HY-133068A	(E)-5-Hydroxyferulic acid		/	Unkown
HY-100642S	3-O-Methyltolcapone-d7	Inhibitor	99.0%	Unkown
HY-169611	Serotonin maleate	Inhibitor	/	Unkown
HY-B1473S2	Serotonin-13C,D4		/	Unkown
HY-109119	Neluxicapone	Inhibitor	/	Unkown
HY-162760	COMT-IN-1	Inhibitor	/	Unkown
HY-151390	hMAO-B/MB-COMT-IN-2	Inhibitor	/	Unkown
HY-168154	COMT-IN-2	Inhibitor	/	Unkown
HY-156069	Methylspinazarin	Inhibitor	/	Unkown
HY-100642	3-O-Methyltolcapone	Inhibitor	99.95%	Unkown
HY-119224	BIA 3-335	Inhibitor	/	Unkown
HY-126194	Tolcapone 3-β-D-glucuronide	Inhibitor	/	Unkown

Species	Symbol	Source	ID
Homo sapiens	COMT	NCBI	NCBI:1312

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