5-Hydroxyferulic acid
Based on 1 Customer Validation
5-Hydroxyferulic acid is a hydroxycinnamic acid and is a metabolite of the phenylpropanoid pathway. 5-Hydroxyferulic acid is a precursor in the biosynthesis of sinapic acid and is also a COMT non-esterifed substrate.
For research use only. We do not sell to patients.
- Purity: 99.43%
- CAS No.: 1782-55-4
- Formula: C10H10O5
- Molecular Weight:210.18
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Metabolism/Protease Compound Library
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All Endogenous Metabolite Isoforms
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Biological Activity
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Human Endogenous Metabolite |
The product of the alfalfa Caffeic acid/5-hydroxyferulic acid 3/5-O-methyltransferase (COMT) catalyzed methylation of 5-Hydroxyferulic acid is sinapic acid. 5-Hydroxyferulic acid O-methyltransferase activities (pkat mg-1 protein) in stem material from COMT downregulates transgenic alfalfa[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1782-55-4
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Appearance Solid
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Molecular Weight 210.18
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Formula C10H10O5
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Color Off-white to light yellow
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SMILES
O=C(O)/C=C/C1=CC(OC)=C(O)C(O)=C1
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (475.78 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. K Parvathi, et al. Substrate Preferences of O-methyltransferases in Alfalfa Suggest New Pathways for 3-O-methylation of Monolignols. Plant J. 2001 Jan;25(2):193-202. [Content Brief]
[2]. S Maury, et al. Tobacco O-methyltransferases Involved in Phenylpropanoid Metabolism. The Different Caffeoyl-Coenzyme A/5-hydroxyferuloyl-coenzyme A 3/5-O-methyltransferase and Caffeic acid/5-hydroxyferulic Acid 3/5-O-methyltransferase Classes Have Distinct Substrate Specificities and Expression Patterns. Plant Physiol. 1999 Sep;121(1):215-24. [Content Brief]
[3]. Inoue, et al. Substrate Preferences of Caffeic acid/5-hydroxyferulic Acid 3/5-O-methyltransferases in Developing Stems of Alfalfa (Medicago Sativa L.). Arch Biochem Biophys. 2000 Mar 1;375(1):175-82. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.7578 mL | 23.7891 mL | 47.5783 mL | 118.9457 mL |
| 5 mM | 0.9516 mL | 4.7578 mL | 9.5157 mL | 23.7891 mL | |
| 10 mM | 0.4758 mL | 2.3789 mL | 4.7578 mL | 11.8946 mL | |
| 15 mM | 0.3172 mL | 1.5859 mL | 3.1719 mL | 7.9297 mL | |
| 20 mM | 0.2379 mL | 1.1895 mL | 2.3789 mL | 5.9473 mL | |
| 25 mM | 0.1903 mL | 0.9516 mL | 1.9031 mL | 4.7578 mL | |
| 30 mM | 0.1586 mL | 0.7930 mL | 1.5859 mL | 3.9649 mL | |
| 40 mM | 0.1189 mL | 0.5947 mL | 1.1895 mL | 2.9736 mL | |
| 50 mM | 0.0952 mL | 0.4758 mL | 0.9516 mL | 2.3789 mL | |
| 60 mM | 0.0793 mL | 0.3965 mL | 0.7930 mL | 1.9824 mL | |
| 80 mM | 0.0595 mL | 0.2974 mL | 0.5947 mL | 1.4868 mL | |
| 100 mM | 0.0476 mL | 0.2379 mL | 0.4758 mL | 1.1895 mL |
5-Hydroxyferulic acid Related Classifications
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