1. Metabolic Enzyme/Protease
    Neuronal Signaling
  2. COMT
    Endogenous Metabolite
  3. 5-Hydroxyferulic acid

5-Hydroxyferulic acid 

Cat. No.: HY-133068 Purity: 99.80%
COA Handling Instructions

5-Hydroxyferulic acid is a hydroxycinnamic acid and is a metabolite of the phenylpropanoid pathway. 5-Hydroxyferulic acid is a precursor in the biosynthesis of sinapic acid and is also a COMT non-esterifed substrate.

For research use only. We do not sell to patients.

5-Hydroxyferulic acid Chemical Structure

5-Hydroxyferulic acid Chemical Structure

CAS No. : 1782-55-4

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5 mg USD 420 In-stock
Estimated Time of Arrival: December 31
10 mg USD 680 Get quote
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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of 5-Hydroxyferulic acid:

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  • Biological Activity

  • Purity & Documentation

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Description

5-Hydroxyferulic acid is a hydroxycinnamic acid and is a metabolite of the phenylpropanoid pathway. 5-Hydroxyferulic acid is a precursor in the biosynthesis of sinapic acid and is also a COMT non-esterifed substrate[1][2][3].

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

The product of the alfalfa Caffeic acid/5-hydroxyferulic acid 3/5-O-methyltransferase (COMT) catalyzed methylation of 5-Hydroxyferulic acid is sinapic acid. 5-Hydroxyferulic acid O-methyltransferase activities (pkat mg-1 protein) in stem material from COMT downregulates transgenic alfalfa[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

210.18

Formula

C10H10O5

CAS No.
SMILES

O=C(O)/C=C/C1=CC(OC)=C(O)C(O)=C1

Structure Classification
Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (475.78 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.7578 mL 23.7891 mL 47.5783 mL
5 mM 0.9516 mL 4.7578 mL 9.5157 mL
10 mM 0.4758 mL 2.3789 mL 4.7578 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation
References
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Product Name:
5-Hydroxyferulic acid
Cat. No.:
HY-133068
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