S1PR1 - sphingosine-1-phosphate receptor 1 Gene
Species: Macaca fascicularis
Gene Type: protein coding
Gene ID: 102127318
About S1PR1
Primary_assembly 1: 122,758,477-122,764,400 reverse strand.Macaca_fascicularis_6.0:CM021939.1
This gene has 2 transcripts (splice variants), 199 orthologues and 16 paralogues.
S1PR1 Products (2)
| mRNA | Protein | Name |
|---|---|---|
| XM_015432061.2 | XP_015287547.1 | sphingosine 1-phosphate receptor 1 |
| XM_005542570.3 | XP_005542627.1 | sphingosine 1-phosphate receptor 1 |
S1PR1 Protein Structure
7tmA_S1PR1_Edg1
7tmA_S1PR1_Edg1: cd15346 (45 - 321)
7tmA_S1PR1_Edg1
7tmA_S1PR1_Edg1: cd15346 (46 - 72)
7tmA_S1PR1_Edg1
7tmA_S1PR1_Edg1: cd15346 (79 - 104)
7tmA_S1PR1_Edg1
7tmA_S1PR1_Edg1: cd15346 (116 - 146)
7tmA_S1PR1_Edg1
7tmA_S1PR1_Edg1: cd15346 (157 - 177)
7tmA_S1PR1_Edg1
7tmA_S1PR1_Edg1: cd15346 (197 - 226)
7tmA_S1PR1_Edg1
7tmA_S1PR1_Edg1: cd15346 (248 - 278)
7tmA_S1PR1_Edg1
7tmA_S1PR1_Edg1: cd15346 (289 - 314)
- 0
- 100
- 200
- 300
- 382 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
sphingosine 1-phosphate receptor 1 |
|
Related Agents
- Approval
- Clinical Phase
- Pre-clinical Phase
Approval
Bioactive Molecules
(5)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-12355 | Siponimod | Agonist | 99.95% | Yes |
| HY-12288 | Ozanimod | Agonist | 99.98% | Yes |
| HY-10569 | Ponesimod | Agonist | 99.78% | Yes |
| HY-12288A | Ozanimod hydrochloride | Modulator | 98.10% | Yes |
| HY-12355A | Siponimod hemifumarate | Agonist | 99.64% | Yes |
Clinical Phase
Bioactive Molecules
(5)
| Cat. No. | Product Name |
Effect
|
Purity |
Phase
|
|---|---|---|---|---|
| HY-17606 | Cenerimod | Agonist | 99.43% | Phase 3 |
| HY-109038 | Mocravimod | Modulator | 98.39% | Phase 3 |
| HY-132847 | Vibozilimod | Agonist | 99.52% | Phase 2 |
| HY-115831 | SAR247799 | Agonist | 99.38% | Phase 1 |
| HY-14976 | CS-0777 | Modulator | / | Phase 1 |
Pre-clinical Phase
Bioactive Molecules
(21)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-W008947 | SEW2871 | Agonist | 99.88% | Unkown |
| HY-111253 | CYM-5478 | Agonist | 99.90% | Unkown |
| HY-136578 | RP101988 | Agonist | 98.80% | Unkown |
| HY-176533 | S1PR5-IN-1 | Inhibitor | 99.58% | Unkown |
| HY-158417 | KSI-6666 | Antagonist | 96.15% | Unkown |
| HY-136576 | RP101075 | Agonist | 99.19% | Unkown |
| HY-147660 | IMMH001 | Agonist | 98.10% | Unkown |
| HY-113934 | L-threo Lysosphingomyelin (d18:1) | Agonist | 98.0% | Unkown |
| HY-14433 | PF-462991 | Agonist | / | Unkown |
| HY-120615 | BMS-520 | Agonist | / | Unkown |
| HY-136577 | RP101442 | Agonist | / | Unkown |
| HY-183578 | TYY-31 | Agonist | / | Unkown |
| HY-181875 | S1PR1/S1PR5 agonist-1 | Inhibitor | / | Unkown |
| HY-119245 | Udifitimod | Modulator | / | Unkown |
| HY-178491 | S1PR1 agonist 3 | Agonist | / | Unkown |
| HY-108492 | TC-SP 14 | Agonist | / | Unkown |
| HY-182626 | CS1P1 | Antagonist | / | Unkown |
| HY-14402 | AMG 369 | Agonist | / | Unkown |
| HY-182375 | (R)-SLB1122168 free base | Inhibitor | / | Unkown |
| HY-182960 | KRP-203 monophosphate | / | Unkown | |
| HY-18334 | GSK-2262167 sodium | Agonist | / | Unkown |
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