CD274 - CD274 molecule Gene
Species: Macaca fascicularis
About CD274
This gene has 4 transcripts (splice variants), 102 orthologues and 11 paralogues.
CD274 Products (3)
| mRNA | Protein | Name |
|---|---|---|
| XM_015437208.2 | XP_015292694.1 | programmed cell death 1 ligand 1 isoform X2 |
| XM_045373223.1 | XP_045229158.1 | programmed cell death 1 ligand 1 isoform X1 |
| XM_005581779.3 | XP_005581836.1 | programmed cell death 1 ligand 1 isoform X3 |
CD274 Protein Structure
IgV_PDl1: cd20947 (20 - 40)
IgV_PDl1: cd20947 (20 - 23)
IgV_PDl1: cd20947 (20 - 129)
IgV_PDl1: cd20947 (25 - 30)
IgV_PDl1: cd20947 (32 - 40)
IgV_PDl1: cd20947 (41 - 52)
IgV_PDl1: cd20947 (52 - 58)
IgV_PDl1: cd20947 (53 - 61)
IgV_PDl1: cd20947 (62 - 73)
IgV_PDl1: cd20947 (62 - 67)
IgV_PDl1: cd20947 (69 - 73)
IgV_PDl1: cd20947 (74 - 115)
IgV_PDl1: cd20947 (83 - 87)
IgV_PDl1: cd20947 (95 - 102)
IgV_PDl1: cd20947 (106 - 116)
IgV_PDl1: cd20947 (116 - 120)
IgV_PDl1: cd20947 (120 - 129)
IgV_PDl1: cd20947 (121 - 129)
Ig: cl11960 (137 - 210)
Ig: cd00096 (150 - 154)
Ig: cd00096 (163 - 172)
Ig: cd00096 (194 - 198)
Ig: cd00096 (205 - 210)
- 0
- 100
- 200
- 303 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
programmed cell death 1 ligand 1 |
|
Recombinant CD274 Proteins
| Cat. No. | Product Name | Accession | Purity |
|---|---|---|---|
| HY-P70564 | PD-L1 Protein, Cynomolgus (HEK293, His) | G7PSE7 (F19-T239) | ≥ 95%, as determined by reducing SDS-PAGE. |
| HY-P71008 | PD-L1 Protein, Cynomolgus (HEK293, Fc) | G7PSE7 (F19-T239) | ≥ 90%, as determined by reducing SDS-PAGE. |
| HY-P77347 | PD-L1 Protein, Cynomolgus/Rhesus Macaque (HEK293, His) | A0A096P1K9/XP_015292694 (F19-T239) | ≥ 95%, as determined by reducing SDS-PAGE. |
| HY-P77348 | PD-L1 Protein, Cynomolgus/Rhesus Macaque (Biotinylated, HEK293, His) | A0A096P1K9/XP_015292694 (F19-T239) | ≥ 95%, as determined by reducing SDS-PAGE. |
Related Agents
- Clinical Phase
- Pre-clinical Phase
Clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Phase
|
|---|---|---|---|---|
| HY-P99903 | Simridarlimab | Inhibitor | 99.81% | Phase 2 |
| HY-P990014 | Danburstotug | Inhibitor | 98.76% | Phase 2 |
| HY-P99698 | Lesabelimab | Inhibitor | 97.34% | Phase 2 |
| HY-P990623 | MDX-1105 | Inhibitor | ≥99.0% | Phase 1 |
| HY-P991354 | GR-1405 | Antagonist | / | Phase 1 |
| HY-P991356 | FAZ-053 | Antagonist | / | Phase 1 |
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS02217 | CD274 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS02218 | Cd274 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS02219 | Cd274 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-14243 | CEP-14083 | Inhibitor | / | Unkown |
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-P990899 | Amostomig | 97.931% | Unkown | |
| HY-P991024 | Solabafusp alfa | Inhibitor | 97.17% | Unkown |
| HY-P991151 | Opamtistomig | Inhibitor | 99.69% | Unkown |
| HY-P991355 | PDL-GEX | Antagonist | / | Unkown |
| HY-P991357 | STT-001 | Antagonist | / | Unkown |
| HY-P992385 | IMM25011 | Inhibitor | / | Unkown |
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