Kmt2b - lysine methyltransferase 2B Gene
Also Known as Mll4; Wbp7; RGD1308331
Species: Rattus norvegicus
Summary
Predicted to enable Histone Methyltransferase activity (H3-K4 specific); unmethylated CpG binding activity; and zinc ion binding activity. Predicted to be involved in histone H3-K4 dimethylation; histone H3-K4 monomethylation; and positive regulation of transcription, DNA-templated. Predicted to act upstream of or within several processes, including DNA methylation-dependent heterochromatin assembly; female gamete generation; and histone H3-K4 trimethylation. Predicted to be located in nucleus. Predicted to be part of Histone Methyltransferase complex. Human ortholog(s) of this gene implicated in colorectal adenocarcinoma; dystonia; and hepatocellular carcinoma. Orthologous to human KMT2B (lysine methyltransferase 2B). [provided by Alliance of Genome Resources, Apr 2022]
Kmt2b Products (3)
| mRNA | Protein | Name |
|---|---|---|
| XM_039093869.1 | XP_038949797.1 | histone-lysine N-methyltransferase 2B isoform X1 |
| XM_008759254.3 | XP_008757476.1 | histone-lysine N-methyltransferase 2B isoform X2 |
| XM_039093878.1 | XP_038949806.1 | histone-lysine N-methyltransferase 2B isoform X3 |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
histone-lysine N-methyltransferase 2B |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS07402 | KMT2B Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS17767 | Kmt2d Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS20975 | Kmt2b Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS27492 | Kmt2b Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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