Atxn3 - ataxin 3 Gene
Also Known as Mjd; ATX3; MJD1; Sca3; ataxin-3; 2210008M02Rik
Species: Mus musculus
Summary
Enables thiol-dependent Deubiquitinase and ubiquitin protein Ligase binding activity. Involved in cellular response to misfolded protein and proteolysis. Acts upstream of or within several processes, including cellular response to heat; exploration behavior; and ubiquitin-dependent protein catabolic process. Located in mitochondrial matrix; mitochondrial membrane; and nuclear inclusion body. Is expressed in several structures, including alimentary system; brain; hemolymphoid system gland; musculature; and testis. Human ortholog(s) of this gene implicated in Machado-Joseph disease. Orthologous to several human genes including ATXN3 (ataxin 3). [provided by Alliance of Genome Resources, Apr 2022]
Atxn3 Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001167914.1 | NP_001161386.1 | ataxin-3 isoform 2 |
| NM_029705.3 | NP_083981.2 | ataxin-3 isoform 1 |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
ataxin-3 |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS01258 | ATXN3 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS01259 | ATXN3L Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS19985 | Atxn3 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS26489 | Atxn3 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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