Nr2f2 - nuclear receptor subfamily 2, group F, member 2 Gene

Also Known as Tfcoup2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 113984

Summary

Enables sequence-specific DNA binding activity. Involved in positive regulation of systemic arterial blood pressure; regulation of transcription, DNA-templated; and response to estradiol. Located in nucleus. Used to study hypertension. Human ortholog(s) of this gene implicated in 46,XX sex reversal 5. Orthologous to human NR2F2 (nuclear receptor subfamily 2 group F member 2). [provided by Alliance of Genome Resources, Apr 2022]

Nr2f2 Products (1)

mRNA Protein Name
NM_080778.2 NP_542956.1 COUP transcription factor 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25687237 RGD
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
12777384 RGD
Biological Process GO Annotation Evidence References Source
involved in positive regulation of systemic arterial blood pressure IMP
IMP: Inferred from mutant phenotype
25687237 RGD
involved in regulation of DNA-templated transcription IMP
IMP: Inferred from mutant phenotype
12777384 RGD
involved in response to estradiol IEP
IEP: Inferred from expression pattern
17109907 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

COUP transcription factor 2

  • ARP-1

  • COUP transcription factor II

  • COUP-TF II

  • COUP-TF2

  • COUPb

  • apolipoprotein A-I regulatory protein 1

  • apolipoprotein AI regulatory protein 1

  • ovalbumin upstream promoter beta nuclear receptor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-156190A NR2F2-IN-1 free base Inhibitor 99.31% Unkown
HY-156190 NR2F2-IN-1 Inhibitor / Unkown
HY-RS09542 NR2F2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20069 Nr2f2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26573 Nr2f2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nr2f2 NCBI NCBI:7026