Acsl3 - acyl-CoA synthetase long-chain family member 3 Gene

Also Known as Acs3; Facl3; LACS 3

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 114024

Summary

Enables arachidonate-CoA Ligase activity. Involved in several processes, including brain development; fatty acid metabolic process; and response to nutrient. Predicted to be located in Golgi apparatus and perinuclear region of cytoplasm. Predicted to be active in endoplasmic reticulum; lipid droplet; and plasma membrane. Human ortholog(s) of this gene implicated in asthma; breast cancer; and prostate Cancer. Orthologous to human ACSL3 (acyl-CoA synthetase long chain family member 3). [provided by Alliance of Genome Resources, Apr 2022]

Acsl3 Products (1)

mRNA Protein Name
NM_057107.2 NP_476448.1 fatty acid CoA ligase Acsl3

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables arachidonate-CoA ligase activity IDA
IDA: Inferred from direct assay
28209804 RGD
enables long-chain fatty acid-CoA ligase activity IDA
IDA: Inferred from direct assay
8663269 RGD
Biological Process GO Annotation Evidence References Source
involved in fatty acid biosynthetic process IDA
IDA: Inferred from direct assay
8663269 RGD
involved in long-chain fatty acid metabolic process IDA
IDA: Inferred from direct assay
28209804 RGD
involved in response to nutrient IEP
IEP: Inferred from expression pattern
16772660 RGD
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
19025659 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

fatty acid CoA ligase Acsl3

  • arachidonate--CoA ligase

  • arachidonate--CoA ligase Acsl3

  • brain acyl-CoA synthetase II

  • fatty acid Coenzyme A ligase, long chain 3

  • long-chain acyl-CoA synthetase 3

  • long-chain-fatty-acid--CoA ligase 3

  • medium-chain acyl-CoA ligase Acsl3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-175328 LIBX-A403 Inhibitor 99.23% Unkown
HY-186096 LP-856866 99.92% Unkown
HY-175327 LIBX-A402 Inhibitor 98.71% Unkown
HY-RS00201 ACSL3 Human Pre-designed siRNA Set A / Unkown
HY-RS18983 Acsl3 Mouse Pre-designed siRNA Set A / Unkown
HY-RS25472 Acsl3 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Acsl3 NCBI NCBI:2181