Insl3 - insulin-like 3 Gene

Also Known as Rlf

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 114215

Summary

Enables G protein-coupled receptor binding activity. Involved in several processes, including male gonad development; oocyte maturation; and positive regulation of cAMP-mediated signaling. Located in extracellular space and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in cryptorchidism. Orthologous to human INSL3 (Insulin like 3). [provided by Alliance of Genome Resources, Apr 2022]

Insl3 Products (1)

mRNA Protein Name
NM_053680.2 NP_446132.1 insulin-like 3 precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
15123806 RGD
involved in negative regulation of apoptotic process IDA
IDA: Inferred from direct assay
15123806 RGD
involved in negative regulation of cell population proliferation IDA
IDA: Inferred from direct assay
15956754 RGD
involved in oocyte maturation IDA
IDA: Inferred from direct assay
15123806 RGD
involved in positive regulation of cAMP/PKA signal transduction IDA
IDA: Inferred from direct assay
12114498 RGD
involved in positive regulation of cell population proliferation IDA
IDA: Inferred from direct assay
12356938 RGD
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
11732985 RGD
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
16037377 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

insulin-like 3

  • Leydig insulin-like peptide relaxin-like factor

  • ley-I-L

  • relaxin-like factor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06840 INSL3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20428 Insl3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26937 Insl3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Insl3 NCBI NCBI:3640