Lyve1 - lymphatic vessel endothelial hyaluronan receptor 1 Gene

Also Known as Xlkd1; Lyve-1; Crsbp-1; 1200012G08Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 114332

Summary

Enables hyaluronic acid binding activity and transmembrane signaling receptor activity. Acts upstream of or within glycosaminoglycan catabolic process. Located in plasma membrane. Is expressed in several structures, including cardiovascular system; gut; hemolymphoid system; meninges; and metanephros. Orthologous to human LYVE1 (lymphatic vessel endothelial hyaluronan receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Lyve1 Products (1)

mRNA Protein Name
NM_053247.4 NP_444477.2 lymphatic vessel endothelial hyaluronic acid receptor 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables cargo receptor activity IDA
IDA: Inferred from direct assay
11278811 MGI
enables hyaluronic acid binding IDA
IDA: Inferred from direct assay
11278811 MGI
enables transmembrane signaling receptor activity IDA
IDA: Inferred from direct assay
11278811 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within glycosaminoglycan catabolic process IDA
IDA: Inferred from direct assay
11278811 MGI
involved in hyaluronan catabolic process IDA
IDA: Inferred from direct assay
11278811 MGI
involved in receptor-mediated endocytosis IDA
IDA: Inferred from direct assay
11278811 MGI
Cellular Component GO Annotation Evidence References Source
located in cell periphery IDA
IDA: Inferred from direct assay
16455951 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
11278811 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

lymphatic vessel endothelial hyaluronic acid receptor 1

  • cell surface retention sequence binding protein-1

  • extra cellular link domain-containing 1

  • extracellular link domain-containing protein 1

  • lymphatic vessel endothelial HA receptor-1

  • lymphatic vessel endothelial HA recptor-1

Recombinant Lyve1 Proteins

Cat. No. Product Name Accession Purity
HY-P74764 LYVE-1 Protein, Mouse (HEK293, Fc) Q8BHC0 (A24-G228) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-175660 KCL-HO-1i Inhibitor / Unkown
HY-RS07929 LYVE1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19020 Lyve1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25509 Lyve1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992437 PF-03475952 / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lyve1 NCBI NCBI:10894