Hdgf - heparin binding growth factor Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 114499

Summary

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II; and protein localization to nucleus. Located in nucleus. Orthologous to human HDGF (heparin binding growth factor). [provided by Alliance of Genome Resources, Apr 2022]

Hdgf Products (1)

mRNA Protein Name
NM_053707.3 NP_446159.1 hepatoma-derived growth factor
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
19162039 RGD
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
19162039 RGD
Biological Process GO Annotation Evidence References Source
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
19162039 RGD
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
19162039 RGD
involved in protein localization to nucleus IDA
IDA: Inferred from direct assay
19162039 RGD
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
19162039 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

hepatoma-derived growth factor

Orthologs Information

Species Symbol Source ID
Homo sapiens Hdgf NCBI NCBI:3068