Tdg - thymine-DNA glycosylase Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 114521

Summary

Enables DNA-binding transcription factor binding activity and protein domain specific binding activity. Involved in negative regulation of transcription by RNA polymerase II. Located in nucleus. Orthologous to human TDG (thymine DNA glycosylase). [provided by Alliance of Genome Resources, Apr 2022]

Tdg Products (2)

mRNA Protein Name
NM_001388503.1 NP_001375432.1 G/T mismatch-specific thymine DNA glycosylase isoform 1
NM_053729.2 NP_446181.2 G/T mismatch-specific thymine DNA glycosylase isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription factor binding IPI
IPI: Inferred from physical interaction
11438542 RGD
enables protein domain specific binding IPI
IPI: Inferred from physical interaction
11438542 RGD
Biological Process GO Annotation Evidence References Source
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
11438542 RGD
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
18945672 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

G/T mismatch-specific thymine DNA glycosylase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-130208 Thiodigalactoside Inhibitor 99.89% Unkown
HY-126181 5-Formylcytosine 96.4% Unkown
HY-181440 TDG-IN-1 Inhibitor / Unkown
HY-RS14329 TDG Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17123 Tdg Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23568 Tdg Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tdg NCBI NCBI:6996