Ddx39b - DExD-box helicase 39B Gene

Also Known as p47; Bat1; Bat1a

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 114612

Summary

Predicted to enable several functions, including ATP-dependent protein binding activity; RNA helicase activity; and snRNA binding activity. Involved in several processes, including positive regulation of cell growth involved in cardiac muscle cell development; positive regulation of macromolecule biosynthetic process; and positive regulation of vascular associated smooth muscle cell proliferation. Located in nuclear matrix. Part of protein-containing complex. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human DDX39B (DExD-box helicase 39B). [provided by Alliance of Genome Resources, Apr 2022]

Ddx39b Products (1)

mRNA Protein Name
NM_133300.3 NP_579834.2 spliceosome RNA helicase Ddx39b

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
10220587 RGD
Biological Process GO Annotation Evidence References Source
involved in liver development IEP
IEP: Inferred from expression pattern
1618789 RGD
involved in positive regulation of DNA biosynthetic process IMP
IMP: Inferred from mutant phenotype
22446327 RGD
involved in positive regulation of cell growth involved in cardiac muscle cell development IMP
IMP: Inferred from mutant phenotype
20116367 RGD
involved in positive regulation of translation IMP
IMP: Inferred from mutant phenotype
20116367 RGD
involved in positive regulation of vascular associated smooth muscle cell proliferation IMP
IMP: Inferred from mutant phenotype
23246467 RGD
Cellular Component GO Annotation Evidence References Source
located in nuclear matrix IDA
IDA: Inferred from direct assay
1618789 RGD
part of protein-containing complex IDA
IDA: Inferred from direct assay
10220587 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

spliceosome RNA helicase Ddx39b

  • 56 kDa U2AF65-associated protein

  • ATP-dependent RNA helicase p47

  • D17H6S81E-1

  • D20H6S81e

  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B

  • DEAD box protein UAP56

  • DEAD-box helicase 39B

  • HLA-B associated transcript 1

  • HLA-B-associated transcript 1A

  • Nuclear RNA

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03645 DDX39B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20544 Ddx39b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27052 Ddx39b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ddx39b NCBI NCBI:7919