Adh7 - alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide Gene

Also Known as Adh3; Adh4; Adh-3; Adt-1; Adh-3e; Adh-3t; Adh3-e; Adh3-t

Species: Mus musculus

Gene Type: protein coding
Gene ID: 11529

Summary

Enables NAD-retinol dehydrogenase activity and alcohol dehydrogenase (NAD+) activity. Acts upstream of or within ethanol catabolic process; retinoic acid metabolic process; and retinol metabolic process. Predicted to be located in plasma membrane. Predicted to be active in cytosol. Is expressed in several structures, including branchial arch; embryo mesenchyme; endocrine gland; neural fold; and reproductive system. Used to study Parkinson's disease. Orthologous to human ADH7 (alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide). [provided by Alliance of Genome Resources, Apr 2022]

Adh7 Products (1)

mRNA Protein Name
NM_009626.4 NP_033756.2 all-trans-retinol dehydrogenase [NAD(+)] ADH7
Molecular Function GO Annotation Evidence References Source
enables alcohol dehydrogenase (NAD+) activity IDA
IDA: Inferred from direct assay
518534 MGI
enables all-trans-retinol dehydrogenase (NAD+) activity IDA
IDA: Inferred from direct assay
3663136 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within ethanol catabolic process IMP
IMP: Inferred from mutant phenotype
10358022 MGI
acts upstream of or within retinoic acid metabolic process IMP
IMP: Inferred from mutant phenotype
10358022 MGI
acts upstream of or within retinol metabolic process IMP
IMP: Inferred from mutant phenotype
10358022 MGI
Cellular Component GO Annotation Evidence References Source
located in intracellular anatomical structure IDA
IDA: Inferred from direct assay
9002638 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

all-trans-retinol dehydrogenase [NAD(+)] ADH7

  • ADH-C2

  • IV ADH

  • alcohol dehydrogenase 3 complex

  • alcohol dehydrogenase 3 temporal

  • alcohol dehydrogenase 4

  • alcohol dehydrogenase class 4 mu/sigma chain

  • alcohol dehydrogenase class IV mu/sigma chain

  • gastric alcohol dehydrogenase

  • omega-hydroxydecanoate

Orthologs Information

Species Symbol Source ID
Homo sapiens Adh7 NCBI NCBI:131