Agtrap - angiotensin II, type I receptor-associated protein Gene

Also Known as AT1R; Atrap; D4Wsu124e; 3300002E14Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 11610

Summary

Enables angiotensin type II receptor activity. Acts upstream of or within regulation of blood pressure. Located in cell cortex and plasma membrane. Is expressed in several structures, including genitourinary system; ileum; liver; lung; and spleen. Used to study acquired Metabolic Disease. Orthologous to human AGTRAP (angiotensin II receptor associated protein). [provided by Alliance of Genome Resources, Apr 2022]

Agtrap Products (2)

mRNA Protein Name
NM_001301281.1 NP_001288210.1 type-1 angiotensin II receptor-associated protein isoform 2
NM_009642.5 NP_033772.2 type-1 angiotensin II receptor-associated protein isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables angiotensin type II receptor activity IMP
IMP: Inferred from mutant phenotype
10425188 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
10358057 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within regulation of blood pressure IMP
IMP: Inferred from mutant phenotype
10425188 MGI
Cellular Component GO Annotation Evidence References Source
located in cell cortex IDA
IDA: Inferred from direct assay
10358057 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
10358057 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

type-1 angiotensin II receptor-associated protein

  • AT1 receptor-associated protein

Agtrap Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Agtrap Q9WVK0 Agtr1a Mus musculus P29754
Imaging
15757644
Intra
Agtrap Q9WVK0 Agtr1a Mus musculus P29754
Y2H
10358057
Intra
Agtrap Q9WVK0 Agtr1a Mus musculus P29754
Pull Down
10358057
Intra
Agtrap Q9WVK0 Agtr1a Mus musculus P29754
IF
10358057
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00472 AGTRAP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21819 Agtrap Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28335 Agtrap Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Agtrap NCBI NCBI:57085