AGTRAP - angiotensin II receptor associated protein Gene

Homo sapiens

Also known as ATRAP

Gene ID: 57085 | Gene type: protein coding

About AGTRAP

Cytogenetic location: 1p36.22 Genomic coordinates (GRCh38): 1:11,736,136-11,750,769 (from NCBI)

This gene has 14 transcripts (splice variants) and 177 orthologues. Ubiquitous expression in bone marrow (RPKM 38.0), prostate (RPKM 28.1) and 25 other tissues.

Summary

This gene encodes a transmembrane protein localized to the plasma membrane and perinuclear vesicular structures. The gene product interacts with the angiotensin II type I receptor and negatively regulates angiotensin II signaling. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

AGTRAP Products(5)

mRNA	Protein	Name
NM_001040194.2	NP_001035284.1	type-1 angiotensin II receptor-associated protein isoform b
NM_001040195.2	NP_001035285.1	type-1 angiotensin II receptor-associated protein isoform c
NM_001040196.2	NP_001035286.1	type-1 angiotensin II receptor-associated protein isoform d
NM_001040197.2	NP_001035287.1	type-1 angiotensin II receptor-associated protein isoform e
NM_020350.5	NP_065083.3	type-1 angiotensin II receptor-associated protein isoform a

AGTRAP Protein Structure

AGTRAP

0
100
159 a.a.

Protein Preferred Names

Protein Names

type-1 angiotensin II receptor-associated protein

AT1 receptor-associated protein

Related Diseases

Diseases

Alias

Hypertensive Retinopathy

Childhood Astrocytic Tumor

Juvenile Astrocytoma

Pediatric Astrocytoma

Hypertension, Essential

Essential Hypertension	Hypertension
High Blood Pressure	Hypertension, Essential, Susceptibility To
Hypertensive Disease	Primary Hypertension
EHT	Hypertension, Salt-Sensitive Essential, Susceptibility To
Hyperpiesia	Idiopathic Hypertension
Hypertensive Disorder	Hypertension, Essential, Susceptibility To, 3
Hypertension, Essential 3	Hypertension, Essential, Salt-Sensitive
Hypertension, Essential, Susceptibility To, 6	Hypertension, Essential 6
Hypertension, Salt-Sensitive Essential	Hypertension, Susceptibility To
Hypertension, Essential, Susceptibility To, 4	Hypertension, Essential 4
Hypertension, Essential, Susceptibility To, 2	Hypertension, Essential 2
Hypertension, Essential, Susceptibility To, 1	Hypertension, Essential 1
Hypertension, Essential, Susceptibility To, 5	Hypertension, Essential 5
Htn	Vascular Hypertensive Disorder
Systemic Primary Arterial Hypertension	Hbp - [High Blood Pressure]
Systemic Arterial Hypertensive Disorder	Elevated Blood Pressure
Arterial Hypertension Nos	Hypertension Nos
Benign Hypertension	Systemic Arterial Hypertension
Systemic Hypertension	Artery Htn
Benign Htn	Vascular Htn
Vascular Hypertension	Cholesterol Hypertension
Cholesterol Htn	Idiopathic Htn
Malignant Hypertension	Malignant Htn
Raised Blood Pressure	Cardiovascular Hypertension
Primary Htn - [Hypertension]	High Arterial Tension
High Blood Pressure Disorder	Ht - [Hypertension]
Htn - [Hypertension]	Hypertensive Vascular Disease
Hypertensive Vascular Degeneration

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00472	AGTRAP Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	AGTRAP	VGNC	VGNC:69604
Rattus norvegicus	AGTRAP	RGD	RGD:1359346
Bos taurus	AGTRAP	VGNC	VGNC:25747
Mus musculus	AGTRAP	MGD	MGI:1339977
Canis familiaris	AGTRAP	VGNC	VGNC:37722

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