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PIMREG - PICALM interacting mitotic regulator Gene

Also Known as CATS; RCS1; FAM64A

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 54478

About PIMREG

Cytogenetic location: 17p13.2 Genomic coordinates (GRCh38): 17:6,444,455-6,451,469 (from NCBI)

This gene has 9 transcripts (splice variants) and 164 orthologues. Broad expression in spleen (RPKM 1.3), small intestine (RPKM 0.7) and 19 other tissues.

Summary

Predicted to be involved in cell division. Located in nucleolus and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

PIMREG Products (2)

mRNA	Protein	Name
NM_001195228.2	NP_001182157.1	protein PIMREG isoform 2
NM_019013.3	NP_061886.2	protein PIMREG isoform 1

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	References	Source
enables protein binding	IPI IPI: Inferred from physical interaction	18482256	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PIMREG Protein Structure

DUF1466

0
100
200
248 a.a.

Protein Preferred Names	Protein Names
protein PIMREG	CALM interacting protein expressed in thymus and spleen

PIMREG Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	PIMREG	Q9BSJ6	KRT40	Homo sapiens	Q6A162	Y2H Prey Pooling	26871637
Intra	PIMREG	Q9BSJ6	KRT40	Homo sapiens	Q6A162	Validated Y2H	26871637
Intra	PIMREG	Q9BSJ6	KRT40	Homo sapiens	Q6A162	Y2H Array	25416956
Intra	PIMREG	Q9BSJ6	KRT40	Homo sapiens	Q6A162	Y2H Array	26871637
Intra	PIMREG	Q9BSJ6	HOOK2	Homo sapiens	Q96ED9-2	Y2H Prey Pooling	26871637
Intra	PIMREG	Q9BSJ6	HOOK2	Homo sapiens	Q96ED9-2	Validated Y2H	26871637
Intra	PIMREG	Q9BSJ6	HOOK2	Homo sapiens	Q96ED9-2	Y2H Array	26871637
Intra	PIMREG	Q9BSJ6	AGTRAP	Homo sapiens	Q6RW13-2	Validated Y2H	26871637
Intra	PIMREG	Q9BSJ6	AGTRAP	Homo sapiens	Q6RW13-2	Y2H Prey Pooling	26871637
Intra	PIMREG	Q9BSJ6	AGTRAP	Homo sapiens	Q6RW13-2	Y2H Array	26871637
Intra	PIMREG	Q9BSJ6	CMTM5	Homo sapiens	Q96DZ9-2	Y2H Prey Pooling	26871637
Intra	PIMREG	Q9BSJ6	CMTM5	Homo sapiens	Q96DZ9-2	Validated Y2H	26871637
Intra	PIMREG	Q9BSJ6	CMTM5	Homo sapiens	Q96DZ9-2	Y2H Array	26871637
Intra	PIMREG	Q9BSJ6	SIAH1	Homo sapiens	Q8IUQ4-2	Validated Y2H	26871637
Intra	PIMREG	Q9BSJ6	SIAH1	Homo sapiens	Q8IUQ4-2	Y2H Prey Pooling	26871637
Intra	PIMREG	Q9BSJ6	SIAH1	Homo sapiens	Q8IUQ4-2	Y2H Array	26871637
Intra	PIMREG	Q9BSJ6	SSX2IP	Homo sapiens	Q9Y2D8	Validated Y2H	25416956
Intra	PIMREG	Q9BSJ6	SSX2IP	Homo sapiens	Q9Y2D8	Y2H Array	25416956
Intra	PIMREG	Q9BSJ6	DOCK8	Homo sapiens	Q8NF50	Validated Y2H	26871637
Intra	PIMREG	Q9BSJ6	DOCK8	Homo sapiens	Q8NF50	Y2H Array	26871637
Intra	PIMREG	Q9BSJ6	DOCK8	Homo sapiens	Q8NF50	Y2H Prey Pooling	26871637
Intra	PIMREG	Q9BSJ6	VPS52	Homo sapiens	Q8N1B4	Validated Y2H	26871637
Intra	PIMREG	Q9BSJ6	VPS52	Homo sapiens	Q8N1B4	Y2H Array	26871637
Intra	PIMREG	Q9BSJ6	VPS52	Homo sapiens	Q8N1B4	Y2H Prey Pooling	26871637
Intra	PIMREG	Q9BSJ6	SPAG5	Homo sapiens	Q96R06	Y2H Prey Pooling	26871637
Intra	PIMREG	Q9BSJ6	SPAG5	Homo sapiens	Q96R06	Validated Y2H	26871637
Intra	PIMREG	Q9BSJ6	SPAG5	Homo sapiens	Q96R06	Y2H Array	26871637
Intra	PIMREG	Q9BSJ6	GOLGA2	Homo sapiens	Q08379	Y2H Prey Pooling	26871637
Intra	PIMREG	Q9BSJ6	GOLGA2	Homo sapiens	Q08379	Validated Y2H	26871637
Intra	PIMREG	Q9BSJ6	GOLGA2	Homo sapiens	Q08379	Y2H Array	26871637
Intra	PIMREG	Q9BSJ6	TFCP2	Homo sapiens	Q12800	Validated Y2H	25416956
Intra	PIMREG	Q9BSJ6	TFCP2	Homo sapiens	Q12800	Y2H Array	25416956
Intra	PIMREG	Q9BSJ6	TRIM27	Homo sapiens	P14373	Y2H Prey Pooling	26871637
Intra	PIMREG	Q9BSJ6	TRIM27	Homo sapiens	P14373	Validated Y2H	26871637
Intra	PIMREG	Q9BSJ6	TRIM27	Homo sapiens	P14373	Y2H Array	26871637
Intra	PIMREG	Q9BSJ6	BEND5	Homo sapiens	Q7L4P6	Validated Y2H	26871637
Intra	PIMREG	Q9BSJ6	BEND5	Homo sapiens	Q7L4P6	Y2H Array	26871637
Intra	PIMREG	Q9BSJ6	BEND5	Homo sapiens	Q7L4P6	Y2H Prey Pooling	26871637
Intra	PIMREG	Q9BSJ6	RINT1	Homo sapiens	Q6NUQ1	Y2H Prey Pooling	26871637
Intra	PIMREG	Q9BSJ6	RINT1	Homo sapiens	Q6NUQ1	Validated Y2H	26871637
Intra	PIMREG	Q9BSJ6	RINT1	Homo sapiens	Q6NUQ1	Y2H Array	26871637
Intra	PIMREG	Q9BSJ6	CEP70	Homo sapiens	Q8NHQ1	Validated Y2H	26871637
Intra	PIMREG	Q9BSJ6	CEP70	Homo sapiens	Q8NHQ1	Y2H Array	26871637
Intra	PIMREG	Q9BSJ6	CEP70	Homo sapiens	Q8NHQ1	Y2H Prey Pooling	25416956
Intra	PIMREG	Q9BSJ6	CEP70	Homo sapiens	Q8NHQ1	Y2H Prey Pooling	26871637
Intra	PIMREG	Q9BSJ6	AGTRAP	Homo sapiens	Q6RW13	Validated Y2H	25416956
Intra	PIMREG	Q9BSJ6	ARMC7	Homo sapiens	Q9H6L4	Validated Y2H	32296183
Intra	PIMREG	Q9BSJ6	CCNDBP1	Homo sapiens	O95273	Y2H Prey Pooling	26871637
Intra	PIMREG	Q9BSJ6	CCNDBP1	Homo sapiens	O95273	Validated Y2H	25416956
Intra	PIMREG	Q9BSJ6	CCNDBP1	Homo sapiens	O95273	Validated Y2H	26871637
Intra	PIMREG	Q9BSJ6	CCNDBP1	Homo sapiens	O95273	Y2H Prey Pooling	25416956
Intra	PIMREG	Q9BSJ6	CCNDBP1	Homo sapiens	O95273	Y2H Array	26871637
Intra	PIMREG	Q9BSJ6	CCNDBP1	Homo sapiens	O95273	Y2H Array	25416956
Intra	PIMREG	Q9BSJ6	MAL2	Homo sapiens	Q969L2	Y2H Array	26871637
Intra	PIMREG	Q9BSJ6	MAL2	Homo sapiens	Q969L2	Y2H Prey Pooling	26871637
Intra	PIMREG	Q9BSJ6	MAL2	Homo sapiens	Q969L2	Validated Y2H	26871637
Intra	PIMREG	Q9BSJ6	PRNP	Homo sapiens	P04156	Protein Array	18482256

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases	Alias
Suppurative Periapical Periodontitis	Periapical Abscess Apical Abscess Suppurative Apical Periodontitis Dentoalveolar Abscess Dental Abscess With Sinus Dentoalveolar Abscess With Sinus Dental Sinus Periapical Abscess Fistula Apical Tooth Abscess Apex Abscess Dental Abscess Nos Infection Of Tooth Nos Abscess Of Tooth Dental Infection Nos
Paragonimiasis	Infection By Paragonimus Lung Fluke Disease Lung Fluke Infection Pulmonary Paragonimiasis Paragonimus Westermani Infection Pulmonary Distomiasis Parasitic Haemoptysis Oriental Lung Fluke Disease Endemic Haemoptysis Paragonimosis Pulmonary Distomatosis Lung Fluke Disorder Infestation By Paragonimus Infection Due To Paragonimus Species Infestation Due To Paragonimus Species Oriental Lung Fluke Infestation Endemic Oriental Haemoptysis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10556	PIMREG Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	PIMREG	VGNC	VGNC:64179
Rattus norvegicus	PIMREG	RGD	RGD:1308747
Macaca mulatta	PIMREG	VGNC	VGNC:99195
Canis familiaris	PIMREG	VGNC	VGNC:44566
Bos taurus	PIMREG	VGNC	VGNC:32902
Mus musculus	PIMREG	MGD	MGI:1924434
Others	PIMREG	NCBI