FHIP1B - FHF complex subunit HOOK interacting protein 1B Gene

Also Known as FHIP; C11orf56; FAM160A2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 84067

Summary

The protein encoded by this gene is part of the FTS/Hook/FHIP (FHF) complex, which can interact with members of the homotypic vesicular protein sorting (HOPS) complex. This interaction suggests that the encoded protein is involved in vesicle trafficking. [provided by RefSeq, Dec 2016]
Ubiquitous expression in small intestine (RPKM 16.8), duodenum (RPKM 16.4) and 25 other tissues.

FHIP1B Products (1)

mRNA Protein Name
NG_052832.1 [RefSeqGene]

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
Biological Process GO Annotation Evidence References Source
involved in early endosome to late endosome transport IMP
IMP: Inferred from mutant phenotype
18799622 GOA
involved in endosome organization IMP
IMP: Inferred from mutant phenotype
18799622 GOA
involved in endosome to lysosome transport IMP
IMP: Inferred from mutant phenotype
18799622 GOA
involved in lysosome organization IMP
IMP: Inferred from mutant phenotype
18799622 GOA
involved in protein localization to perinuclear region of cytoplasm IMP
IMP: Inferred from mutant phenotype
32073997 GOA
Cellular Component GO Annotation Evidence References Source
part of FHF complex IDA
IDA: Inferred from direct assay
18799622 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FHIP1B Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
FHIP1B Q8N612 RAB5B Homo sapiens P61020
Anti Tag CoIP
34882091
Intra
FHIP1B Q8N612 RAB5B Homo sapiens P61020
Confocal
34882091
Intra
FHIP1B Q8N612 RAB5B Homo sapiens P61020
Pull Down
34882091
Intra
FHIP1B Q8N612 RAB5B Homo sapiens P61020
BioID
34882091
Intra
FHIP1B Q8N612 REEP6 Homo sapiens Q96HR9
Y2H Prey Pooling
25416956
Intra
FHIP1B Q8N612 REEP6 Homo sapiens Q96HR9
Validated Y2H
25416956
Intra
FHIP1B Q8N612 REEP6 Homo sapiens Q96HR9
Y2H Pooling
16189514
Cross: Cross-species interaction Intra: Intraspecies interaction

FHIP1B Antibodies

Cat. No. Product Name Application Reactivity
HY-P86258 FAM160A2 Antibody (YA5950) WB Human