2. Gene
  3. RAB5B - RAB5B, member RAS oncogene family Gene

RAB5B - RAB5B, member RAS oncogene family Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 5869 | Gene type: protein coding

About RAB5B

Cytogenetic location: 12q13.2 Genomic coordinates (GRCh38): 12:55,973,949-55,996,683 (from NCBI)

This gene has 11 transcripts (splice variants), 135 orthologues and 68 paralogues. Ubiquitous expression in brain (RPKM 35.5), esophagus (RPKM 35.2) and 25 other tissues.

Summary

Enables GDP binding activity; GTP-dependent protein binding activity; and GTPase activity. Involved in antigen processing and presentation and plasma membrane to endosome transport. Located in endosome and extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

RAB5B Products(5)

mRNA Protein Name
NM_001252036.2 NP_001238965.1 ras-related protein Rab-5B isoform 1
NM_001252037.2 NP_001238966.1 ras-related protein Rab-5B isoform 2
NM_001414457.1 NP_001401386.1 ras-related protein Rab-5B isoform 1
NM_001414458.1 NP_001401387.1 ras-related protein Rab-5B isoform 3
NM_002868.4 NP_002859.1 ras-related protein Rab-5B isoform 1

RAB5B Protein Structure

Ras

Ras: Ras family (22 - 181)

  • 0
  • 100
  • 200
  • 215 a.a.
Protein Preferred Names Protein Names

ras-related protein Rab-5B

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11572 RAB5B Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus RAB5B MGD MGI:105938
Bos taurus RAB5B VGNC VGNC:33659
Macaca mulatta RAB5B VGNC VGNC:81546
Rattus norvegicus RAB5B RGD RGD:1306489
Canis familiaris RAB5B VGNC VGNC:45292
Felis catus RAB5B VGNC VGNC:97593