RMDN2 - regulator of microtubule dynamics 2 Gene

Also Known as RMD2; RMD4; RMD-2; FAM82A; BLOCK18; FAM82A1; PRO34163; PYST9371

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 151393

Summary

Enables microtubule binding activity. Located in cytosol; mitotic spindle pole; and spindle microtubule. [provided by Alliance of Genome Resources, Jun 2026]
Broad expression in adrenal (RPKM 5.4), spleen (RPKM 2.9) and 22 other tissues.

RMDN2 Products (6)

mRNA Protein Name
NM_001170791.3 NP_001164262.1 regulator of microtubule dynamics protein 2 isoform 2
NM_001170792.3 NP_001164263.1 regulator of microtubule dynamics protein 2 isoform 2
NM_001170793.3 NP_001164264.1 regulator of microtubule dynamics protein 2 isoform 3
NM_001322211.2 NP_001309140.1 regulator of microtubule dynamics protein 2 isoform 2
NM_001322212.2 NP_001309141.1 regulator of microtubule dynamics protein 2 isoform 4
NM_144713.5 NP_653314.3 regulator of microtubule dynamics protein 2 isoform 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables microtubule binding IDA
IDA: Inferred from direct assay
18070910 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
Cellular Component GO Annotation Evidence References Source
located in mitotic spindle pole IDA
IDA: Inferred from direct assay
18070910 GOA
located in spindle microtubule IDA
IDA: Inferred from direct assay
18070910 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RMDN2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
RMDN2 Q96LZ7 VAPB Homo sapiens Q53XM7
Y2H Array
25416956
Intra
RMDN2 Q96LZ7 VAPB Homo sapiens Q53XM7
Validated Y2H
25416956
Intra
RMDN2 Q96LZ7 TNFRSF10D Homo sapiens Q9UBN6
Validated Y2H
32296183
Intra
RMDN2 Q96LZ7 TNFRSF10D Homo sapiens Q9UBN6
Y2H Prey Pooling
32296183
Intra
RMDN2 Q96LZ7 TNFRSF10D Homo sapiens Q9UBN6
Y2H Array
32296183
Intra
RMDN2 Q96LZ7 HSD17B11 Homo sapiens Q8NBQ5
Y2H Array
32296183
Intra
RMDN2 Q96LZ7 HSD17B11 Homo sapiens Q8NBQ5
Y2H Prey Pooling
32296183
Intra
RMDN2 Q96LZ7 RMDN3 Homo sapiens Q96TC7
Anti Tag CoIP
33961781
Intra
RMDN2 Q96LZ7 RMDN3 Homo sapiens Q96TC7
Anti Tag CoIP
28514442
Intra
RMDN2 Q96LZ7 VAPA Homo sapiens Q9P0L0
Y2H Prey Pooling
32296183
Intra
RMDN2 Q96LZ7 VAPA Homo sapiens Q9P0L0
Validated Y2H
32296183
Intra
RMDN2 Q96LZ7 VAPA Homo sapiens Q9P0L0
Y2H Array
32296183
Intra
RMDN2 Q96LZ7 AGTRAP Homo sapiens Q6RW13-2
Y2H Prey Pooling
32296183
Intra
RMDN2 Q96LZ7 AGTRAP Homo sapiens Q6RW13-2
Y2H Array
32296183
Intra
RMDN2 Q96LZ7 CMTM5 Homo sapiens Q96DZ9-2
Y2H Prey Pooling
32296183
Intra
RMDN2 Q96LZ7 CMTM5 Homo sapiens Q96DZ9-2
Y2H Array
32296183
Intra
RMDN2 Q96LZ7 RTN3 Homo sapiens O95197-3
Y2H Prey Pooling
32296183
Intra
RMDN2 Q96LZ7 RTN3 Homo sapiens O95197-3
Y2H Array
32296183
Intra
RMDN2 Q96LZ7 VAPB Homo sapiens O95292
Y2H Array
32296183
Intra
RMDN2 Q96LZ7 VAPB Homo sapiens O95292
Y2H Prey Pooling
32296183
Intra
RMDN2 Q96LZ7 RDH10 Homo sapiens Q8IZV5
Y2H Array
32296183
Intra
RMDN2 Q96LZ7 RDH10 Homo sapiens Q8IZV5
Y2H Prey Pooling
32296183
Intra
RMDN2 Q96LZ7 CMTM5 Homo sapiens Q96DZ9
Y2H Array
25416956
Intra
RMDN2 Q96LZ7 SAR1A Homo sapiens Q9NR31
Y2H Prey Pooling
32296183
Intra
RMDN2 Q96LZ7 SAR1A Homo sapiens Q9NR31
Validated Y2H
32296183
Intra
RMDN2 Q96LZ7 SAR1A Homo sapiens Q9NR31
Y2H Array
32296183
Intra
RMDN2 Q96LZ7 DIABLO Homo sapiens Q9NR28
Y2H Array
32296183
Intra
RMDN2 Q96LZ7 DIABLO Homo sapiens Q9NR28
Y2H Prey Pooling
32296183
Intra
RMDN2 Q96LZ7 DIABLO Homo sapiens Q9NR28
Validated Y2H
32296183
Intra
RMDN2 Q96LZ7 STX1A Homo sapiens Q16623
Y2H Array
32296183
Intra
RMDN2 Q96LZ7 STX1A Homo sapiens Q16623
Y2H Prey Pooling
32296183
Intra
RMDN2 Q96LZ7 THAP4 Homo sapiens Q8WY91
Y2H Prey Pooling
32296183
Intra
RMDN2 Q96LZ7 THAP4 Homo sapiens Q8WY91
Y2H Array
32296183
Intra
RMDN2 Q96LZ7 AGTRAP Homo sapiens Q6RW13
Y2H Prey Pooling
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12013 RMDN3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22777 Rmdn3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29291 Rmdn3 Rat Pre-designed siRNA Set A / Unkown