PCTP - phosphatidylcholine transfer protein Gene

Homo sapiens

Also known as PC-TP; STARD2

Gene ID: 58488 | Gene type: protein coding

About PCTP

Cytogenetic location: 17q22 Genomic coordinates (GRCh38): 17:55,751,051-55,852,715 (from NCBI)

This gene has 8 transcripts (splice variants), 212 orthologues and 2 paralogues. Ubiquitous expression in liver (RPKM 9.3), placenta (RPKM 5.2) and 24 other tissues.

Summary

Enables phosphatidylcholine binding activity and phosphatidylcholine transporter activity. Involved in phospholipid transport. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

PCTP Products(4)

mRNA	Protein	Name
NM_001102402.3	NP_001095872.1	phosphatidylcholine transfer protein isoform 2
NM_001330377.2	NP_001317306.1	phosphatidylcholine transfer protein isoform 3
NM_001330378.3	NP_001317307.1	phosphatidylcholine transfer protein isoform 4
NM_021213.4	NP_067036.2	phosphatidylcholine transfer protein isoform 1

PCTP Protein Structure

START

0
100
200
214 a.a.

Protein Preferred Names

Protein Names

phosphatidylcholine transfer protein

START domain-containing protein 2

Related Diseases

Diseases

Alias

Leukoencephalopathy With Vanishing White Matter

Cree Leukoencephalopathy	Vanishing White Matter Disease
Ovarioleukodystrophy	Vanishing White Matter Leukodystrophy
Childhood Ataxia With Central Nervous System Hypomyelinization	Cach
Cach Syndrome	Myelinosis Centralis Diffusa
VWM	Cle
Childhood Ataxia With Central Nervous System Hypomyelination	Childhood Ataxia With Diffuse Central Nervous System Hypomyelination
Cach/Vwm	Cach/Vwm Syndrome
Childhood Ataxia With Central Nervous System Hypomyelination/Vanishing White Matter	Cree Leukoencehalopathy
Late Infantile Cach Syndrome	Juvenile Or Adult Cach Syndrome
Congenital Or Early Infantile Cach Syndrome	Leukodystrophy With Vanishing White Matter

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-153754	Phosphatidylcholine transfer protein inhibitor-1	98.01%	Unkown
HY-RS10178	PCTP Human Pre-designed siRNA Set A	/	Unkown
HY-110260	LDN-193188	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	PCTP	RGD	RGD:3276
Canis familiaris	PCTP	VGNC	VGNC:44326
Mus musculus	PCTP	MGD	MGI:107375
Macaca mulatta	PCTP	VGNC	VGNC:75789
Felis catus	PCTP	VGNC	VGNC:68738

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