MOGAT1 - monoacylglycerol O-acyltransferase 1 Gene

Also Known as MGAT1; DGAT2L; DGAT2L1

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 116255

About MOGAT1

Cytogenetic location: 2q36.1 Genomic coordinates (GRCh38): 2:222,671,658-222,709,930 (from NCBI)

This gene has 1 transcript (splice variant), 219 orthologues and 6 paralogues. Biased expression in gall bladder (RPKM 7.8) and fat (RPKM 0.6).

Summary

Acyl-CoA:monoacylglycerol Acyltransferase (MOGAT; EC 2.3.1.22) catalyzes the synthesis of diacylglycerols, the precursor of physiologically important lipids such as triacylglycerol and Phospholipids (Yen et al., 2002 [PubMed 12077311]).[supplied by OMIM, Mar 2008]

MOGAT1 Products (1)

mRNA Protein Name
NM_058165.3 NP_477513.2 2-acylglycerol O-acyltransferase 1

MOGAT1 Protein Structure

DAGAT

DAGAT: Diacylglycerol acyltransferase (41 - 335)

  • 0
  • 100
  • 200
  • 300
  • 335 a.a.
Protein Preferred Names Protein Names

2-acylglycerol O-acyltransferase 1

  • acyl-CoA:monoacylglycerol acyltransferase 1

関連疾患

Diseases Alias
Lipodystrophy, Congenital Generalized, Type 1

  • Congenital Generalized Lipodystrophy Type 1

  • Bscl1

  • CGL1

  • Berardinelli-Seip Congenital Lipodystrophy, Type 1

  • Brunzell Syndrome Agpat2-Related

  • Berardinelli-Seip Congenital Lipodystrophy Type 1

  • Lipodystrophy, Berardinelli-Seip Congenital, Type 1

  • Brunzell Syndrome, Agpat2-Related

  • Agpat2-Related Brunzell Syndrome

  • Congenital Generalized Lipodystrophy 1

  • Berardinelli-Seip Syndrome

  • Lipoatrophic Diabetes

  • Lipodystrophy Berardinelli Type

  • Total Lipodystrophy And Acromegaloid Gigantism

  • Lipodystrophy, Generalized, Congenital, Type 1

  • Familial Generalized Lipodystrophy

  • Lipoatrophic Diabetes Mellitus

  • Familial Partial Lipodystrophy, Type 2
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS08584 MOGAT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Felis catus MOGAT1 VGNC VGNC:80283
Canis familiaris MOGAT1 VGNC VGNC:43308
Mus musculus MOGAT1 MGD MGI:1915643
Macaca mulatta MOGAT1 VGNC VGNC:74791
Bos taurus MOGAT1 VGNC VGNC:31550
Rattus norvegicus MOGAT1 RGD RGD:1311644
Others MOGAT1 NCBI