Lct - lactase Gene

Also Known as Lph

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 116569

Summary

Enables lactase activity and transferase activity. Involved in several processes, including response to estrogen; response to iron(II) ion; and response to lead ion. Located in brush border. Used to study diarrhea. Biomarker of colitis. Human ortholog(s) of this gene implicated in congenital lactase deficiency. Orthologous to human LCT (lactase). [provided by Alliance of Genome Resources, Apr 2022]

Lct Products (1)

mRNA Protein Name
NM_053841.1 NP_446293.1 lactase/phlorizin hydrolase preproprotein

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables beta-glucosidase activity IDA
IDA: Inferred from direct assay
4752949 RGD
enables galactosylceramidase activity IDA
IDA: Inferred from direct assay
4752949 RGD
enables glucosylceramidase activity IDA
IDA: Inferred from direct assay
4752949 RGD
enables lactase activity IDA
IDA: Inferred from direct assay
4752949 RGD
enables phlorizin hydrolase activity IDA
IDA: Inferred from direct assay
4752949 RGD
enables transferase activity IDA
IDA: Inferred from direct assay
12023280 RGD
Biological Process GO Annotation Evidence References Source
involved in cellobiose catabolic process IDA
IDA: Inferred from direct assay
4752949 RGD
involved in glycosylceramide catabolic process IDA
IDA: Inferred from direct assay
4752949 RGD
involved in lactose catabolic process IDA
IDA: Inferred from direct assay
4752949 RGD
involved in response to estrogen IEP
IEP: Inferred from expression pattern
16396664 RGD
involved in response to ethanol IDA
IDA: Inferred from direct assay
15849819 RGD
involved in response to hormone IEP
IEP: Inferred from expression pattern
17190105 RGD
involved in response to hypoxia IDA
IDA: Inferred from direct assay
12773704 RGD
involved in response to iron(II) ion IDA
IDA: Inferred from direct assay
16081762 RGD
involved in response to lead ion IDA
IDA: Inferred from direct assay
16092086 RGD
involved in response to nickel cation IDA
IDA: Inferred from direct assay
16819762 RGD
involved in response to nutrient IDA
IDA: Inferred from direct assay
16497337 RGD
involved in response to starvation IEP
IEP: Inferred from expression pattern
17190105 RGD
involved in response to sucrose IEP
IEP: Inferred from expression pattern
17190105 RGD
involved in response to xenobiotic stimulus IDA
IDA: Inferred from direct assay
17147060 RGD
Cellular Component GO Annotation Evidence References Source
located in brush border IDA
IDA: Inferred from direct assay
12023280 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

lactase/phlorizin hydrolase

  • lactase-glycosylceramidase

  • lactase-phlorizin hydrolase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-D3009 LCE1 / Unkown
HY-RS07565 LCT Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19864 Lct Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26363 Lct Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lct NCBI NCBI:3938