Lman1 - lectin, mannose-binding, 1 Gene

Also Known as p58

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 116666

Summary

Enables identical protein binding activity. Predicted to be involved in several processes, including Golgi organization; endoplasmic reticulum to Golgi vesicle-mediated transport; and negative regulation of protein targeting to mitochondrion. Located in Golgi apparatus; endoplasmic reticulum; and endoplasmic reticulum-Golgi intermediate compartment. Is integral component of membrane. Human ortholog(s) of this gene implicated in factor V deficiency and factor XIII deficiency. Orthologous to human LMAN1 (lectin, mannose binding 1). [provided by Alliance of Genome Resources, Apr 2022]

Lman1 Products (1)

mRNA Protein Name
NM_053886.2 NP_446338.1 protein ERGIC-53 precursor
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IDA
IDA: Inferred from direct assay
16257008 RGD
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum-Golgi intermediate compartment IDA
IDA: Inferred from direct assay
16257008 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
33239744 RGD
is active in postsynaptic Golgi apparatus IDA
IDA: Inferred from direct assay
33239744 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein ERGIC-53

  • ER-Golgi intermediate compartment 53 kDa protein

  • endoplasmic reticulum-golgi intermediate compartment protein 53

Orthologs Information

Species Symbol Source ID
Homo sapiens Lman1 NCBI NCBI:3998