Ube2n - ubiquitin-conjugating enzyme E2N Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 116725

Summary

Enables ubiquitin-protein transferase activity. Predicted to be involved in several processes, including DNA repair; protein ubiquitination; and regulation of protein modification process. Predicted to act upstream of or within ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm; fibrillar center; and nucleoplasm. Predicted to be part of UBC13-MMS2 complex; UBC13-UEV1A complex; and ubiquitin Ligase complex. Predicted to be active in nucleus. Orthologous to several human genes including UBE2N (ubiquitin conjugating enzyme E2 N). [provided by Alliance of Genome Resources, Apr 2022]

Ube2n Products (1)

mRNA Protein Name
NM_053928.2 NP_446380.1 ubiquitin-conjugating enzyme E2 N

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables ubiquitin-protein transferase activity IMP
IMP: Inferred from mutant phenotype
11882492 RGD
Biological Process GO Annotation Evidence References Source
involved in regulation protein catabolic process at postsynapse IDA
IDA: Inferred from direct assay
28973854 RGD
involved in regulation protein catabolic process at postsynapse IEP
IEP: Inferred from expression pattern
28973854 RGD
involved in regulation protein catabolic process at postsynapse IMP
IMP: Inferred from mutant phenotype
28973854 RGD
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
28973854 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
28973854 RGD
is active in postsynapse IDA
IDA: Inferred from direct assay
28973854 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ubiquitin-conjugating enzyme E2 N

  • E2 ubiquitin-conjugating enzyme N

  • bendless protein

  • bendless-like ubiquitin-conjugating enzyme

  • ubiquitin carrier protein N

  • ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)

  • ubiquitin-conjugating enzyme E2N (homologous to yeast UBC13)

  • ubiquitin-

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-13811 NSC697923 99.90% Unkown
HY-153775 UC-764864 99.89% Unkown
HY-RS15356 UBE2N Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18303 Ube2n Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24781 Ube2n Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ube2n NCBI NCBI:7334