ART5 - ADP-ribosyltransferase 5 Gene

Also Known as ARTC5

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 116969

About ART5

Cytogenetic location: 11p15.4 Genomic coordinates (GRCh38): 11:3,638,512-3,642,379 (from NCBI)

This gene has 5 transcripts (splice variants), 615 orthologues and 3 paralogues. Biased expression in testis (RPKM 6.5), ovary (RPKM 2.3) and 5 other tissues.

Summary

The protein encoded by this gene belongs to the ARG-specific ADP-ribosyltransferase family. Proteins in this family regulate the function of target proteins by attaching ADP-ribose to specific amino acid residues in their target proteins. The mouse homolog lacks a glycosylphosphatidylinositol-anchor signal sequence and is predicted to be a secretory enzyme. Several transcripts encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

ART5 Products (3)

mRNA Protein Name
NM_001079536.2 NP_001073004.1 ecto-ADP-ribosyltransferase 5 isoform a precursor
NM_001297668.2 NP_001284597.1 ecto-ADP-ribosyltransferase 5 isoform b precursor
NM_053017.5 NP_443750.2 ecto-ADP-ribosyltransferase 5 isoform a precursor

ART5 Protein Structure

ART

ART: NAD:arginine ADP-ribosyltransferase (30 - 254)

  • 0
  • 100
  • 200
  • 291 a.a.
Protein Preferred Names Protein Names

ecto-ADP-ribosyltransferase 5

  • ADP-ribosyltransferase C2 and C3 toxin-like 5

ART5 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ART5 Q96L15 PGRMC2 Homo sapiens O15173
Y2H Array
32296183
Intra
ART5 Q96L15 PGRMC2 Homo sapiens O15173
Y2H Prey Pooling
32296183
Intra
ART5 Q96L15 PGRMC2 Homo sapiens O15173
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01047 ART5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta ART5 VGNC VGNC:69890
Mus musculus ART5 MGD MGI:107948
Rattus norvegicus ART5 RGD RGD:628834
Canis familiaris ART5 VGNC VGNC:38149
Felis catus ART5 VGNC VGNC:59950
Others ART5 NCBI