UBR5 - Ubr5 ubiquitin protein ligase E3 component n-recognin 5 Gene

Also Known as Dd5; Rat100

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 117060

Summary

Enables protein domain specific binding activity and ubiquitin protein Ligase activity. Involved in protein ubiquitination. Located in cytosol. Human ortholog(s) of this gene implicated in invasive ductal carcinoma. Orthologous to human UBR5 (ubiquitin protein Ligase E3 component n-recognin 5). [provided by Alliance of Genome Resources, Apr 2022]

UBR5 Products (5)

mRNA Protein Name
XM_039080165.1 XP_038936093.1 E3 ubiquitin-protein ligase UBR5 isoform X3
XM_039080166.1 XP_038936094.1 E3 ubiquitin-protein ligase UBR5 isoform X4
XM_039080164.1 XP_038936092.1 E3 ubiquitin-protein ligase UBR5 isoform X2
XM_039080163.1 XP_038936091.1 E3 ubiquitin-protein ligase UBR5 isoform X1
XM_017595225.2 XP_017450714.1 E3 ubiquitin-protein ligase UBR5 isoform X5

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein domain specific binding IDA
IDA: Inferred from direct assay
16554297 RGD
enables ubiquitin protein ligase activity IDA
IDA: Inferred from direct assay
12239083 RGD
enables ubiquitin protein ligase activity IMP
IMP: Inferred from mutant phenotype
7708685 RGD
Biological Process GO Annotation Evidence References Source
involved in protein ubiquitination IDA
IDA: Inferred from direct assay
12239083 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase UBR5

  • E3 ubiquitin-protein ligase UBR5-like

  • E3 ubiquitin-protein ligase, HECT domain-containing 1

  • HECT-type E3 ubiquitin transferase UBR5

  • hyperplastic discs protein homolog

  • progestin-induced protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15390 UBR5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-168869 Tamoxifen-PEG-Clozapine Degrader / Unkown
HY-RS18504 Ubr5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24986 Ubr5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens UBR5 NCBI NCBI:51366