Apoa4 - apolipoprotein A-IV Gene
Also Known as Apoa-4
Species: Mus musculus
Summary
Predicted to enable several functions, including cation binding activity; Cholesterol binding activity; and Cholesterol transfer activity. Involved in innate immune response in mucosa. Acts upstream of or within regulation of intestinal Cholesterol absorption and response to stilbenoid. Located in extracellular space. Is expressed in embryo and liver. Human ortholog(s) of this gene implicated in Alzheimer's disease; colitis; myocardial infarction; and ulcerative colitis. Orthologous to human APOA4 (Apolipoprotein A4). [provided by Alliance of Genome Resources, Apr 2022]
Apoa4 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_007468.2 | NP_031494.2 | apolipoprotein A-IV precursor |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in innate immune response in mucosa |
IMP
IMP: Inferred from mutant phenotype
|
15254593 | MGI |
| acts upstream of or within regulation of intestinal cholesterol absorption |
IMP
IMP: Inferred from mutant phenotype
|
9323588 | MGI |
| involved in response to stilbenoid |
IEP
IEP: Inferred from expression pattern
|
17086191 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in extracellular space |
IDA
IDA: Inferred from direct assay
|
7798939 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
apolipoprotein A-IV |
|
|
Recombinant Apoa4 Proteins
| Cat. No. | Product Name | Accession | Purity |
|---|---|---|---|
| HY-P71715 | ApoA-IV Protein, Mouse (P.pastoris, His) | P06728 (E21-S395) | ≥ 90%, as determined by reducing SDS-PAGE. |