Bcl2l10 - Bcl2-like 10 Gene

Also Known as Boo; Diva

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12049

About Bcl2l10

Chromosome 9: 75,255,040-75,258,931 forward strand.GRCm39:CM001002.3

This gene has 1 transcript (splice variant), 23 orthologues and is associated with 1 phenotype. Biased expression in ovary adult (RPKM 8.8) and subcutaneous fat pad adult (RPKM .4).

Summary

Enables identical protein binding activity. Acts upstream of or within negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; negative regulation of intrinsic apoptotic signaling pathway; and positive regulation of apoptotic process. Located in membrane. Is expressed in early conceptus; epididymis; meninges; and ovary. Human ortholog(s) of this gene implicated in multiple myeloma; myelodysplastic syndrome; and stomach carcinoma. Orthologous to human BCL2L10 (BCL2 like 10). [provided by Alliance of Genome Resources, Apr 2022]

Bcl2l10 Products (1)

mRNA Protein Name
NM_013479.2 NP_038507.1 bcl-2-like protein 10

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
9878060 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
17532299 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of extrinsic apoptotic signaling pathway in absence of ligand IDA
IDA: Inferred from direct assay
9878060 MGI
acts upstream of intrinsic apoptotic signaling pathway IDA
IDA: Inferred from direct assay
9878060 MGI
involved in microtubule organizing center organization IMP
IMP: Inferred from mutant phenotype
27753540 MGI
acts upstream of or within negative regulation of extrinsic apoptotic signaling pathway in absence of ligand IDA
IDA: Inferred from direct assay
9878060 MGI
acts upstream of or within negative regulation of intrinsic apoptotic signaling pathway IDA
IDA: Inferred from direct assay
9878060 MGI
acts upstream of or within positive regulation of apoptotic process IDA
IDA: Inferred from direct assay
9829980 MGI
Cellular Component GO Annotation Evidence References Source
located in membrane IDA
IDA: Inferred from direct assay
9878060 MGI
located in spindle IDA
IDA: Inferred from direct assay
27753540 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Bcl2l10 Protein Structure

BCL

BCL: smart00337 (41 - 150)

  • 0
  • 100
  • 191 a.a.
Protein Preferred Names Protein Names

bcl-2-like protein 10

  • anti-apoptotic protein Boo

  • apoptosis regulator Bcl-B

  • bcl-2 homolog Diva

  • bcl2-L-10

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-150540 Bcl-2-IN-10 / Unkown
HY-RS01424 BCL2L10 Human Pre-designed siRNA Set A / Unkown
HY-RS01425 Bcl2l10 Mouse Pre-designed siRNA Set A / Unkown
HY-RS01426 Bcl2l10 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bcl2l10 NCBI NCBI:10017