Cxcr5 - chemokine (C-X-C motif) receptor 5 Gene

Also Known as Blr1; Gpcr6; MDR15; CXC-R5; CXCR-5

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12145

Summary

Predicted to enable C-C chemokine binding activity and C-C Chemokine Receptor activity. Acts upstream of or within leukocyte chemotaxis and lymph node development. Located in external side of plasma membrane. Is expressed in central nervous system and retina. Orthologous to human CXCR5 (C-X-C motif Chemokine Receptor 5). [provided by Alliance of Genome Resources, Apr 2022]

Cxcr5 Products (1)

mRNA Protein Name
NM_007551.3 NP_031577.2 C-X-C chemokine receptor type 5

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within leukocyte chemotaxis IDA
IDA: Inferred from direct assay
25348153 MGI
acts upstream of or within lymph node development IMP
IMP: Inferred from mutant phenotype
12732660 MGI
Cellular Component GO Annotation Evidence References Source
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
23583643 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

C-X-C chemokine receptor type 5

  • burkitt lymphoma receptor 1 homolog

  • chemochine (C-X-C motif) receptor 5

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-163480 PF-06835375 Antagonist 97.71% Phase 2

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-122197 ML339 Antagonist 99.88% Unkown
HY-182774 YU241279 Inhibitor 99.58% Unkown
HY-RS03409 CXCR5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174724 Human CXCR5 mRNA / Unkown
HY-RS16995 Cxcr5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23438 Cxcr5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991567 VX5 Modulator 96.19% Unkown
HY-P991227 Anti-CD185/CXCR5 Antibody Inhibitor 97.41% Unkown
HY-P991477 HFB-100204 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cxcr5 NCBI NCBI:643