Bnc1 - basonuclin 1 Gene

Also Known as Bnc

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12173

Summary

Predicted to enable DNA-binding transcription activator activity and rDNA binding activity. Acts upstream of or within several processes, including positive regulation of epithelial cell proliferation; regulation of transcription, DNA-templated; and wound healing. Located in cytoplasm and nucleolus. Is expressed in several structures, including alimentary system; branchial arch; gonad; outer layer of bladder; and skin. Human ortholog(s) of this gene implicated in primary ovarian insufficiency 16. Orthologous to human BNC1 (basonuclin 1). [provided by Alliance of Genome Resources, Apr 2022]

Bnc1 Products (1)

mRNA Protein Name
NM_007562.2 NP_031588.2 zinc finger protein basonuclin-1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
23707421 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within chromosome organization IMP
IMP: Inferred from mutant phenotype
16624857 MGI
acts upstream of epithelial cell proliferation IMP
IMP: Inferred from mutant phenotype
17971852 MGI
acts upstream of or within positive regulation of epithelial cell proliferation IMP
IMP: Inferred from mutant phenotype
17971852 MGI
acts upstream of or within regulation of transcription by RNA polymerase I IMP
IMP: Inferred from mutant phenotype
16624857 MGI
acts upstream of or within regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
16624857 MGI
acts upstream of or within wound healing IMP
IMP: Inferred from mutant phenotype
17971852 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
9810705 MGI
located in nucleolus IDA
IDA: Inferred from direct assay
11152639 MGI
located in nucleus IDA
IDA: Inferred from direct assay
9810705 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

zinc finger protein basonuclin-1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-111000 BNC-1 / Unkown
HY-RS01090 ASIC2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01560 BNC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18465 Bnc1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24946 Bnc1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bnc1 NCBI NCBI:646