Cbr1 - carbonyl reductase 1 Gene

Also Known as CR; Cbr; PG-9-KR

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12408

Summary

Predicted to enable carbonyl reductase (NADPH) activity and oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor. Predicted to be involved in several processes, including phylloquinone catabolic process; prostaglandin catabolic process; and response to progesterone. Part of subapical complex. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and sensory organ. Orthologous to human CBR1 (carbonyl reductase 1). [provided by Alliance of Genome Resources, Apr 2022]

Cbr1 Products (1)

mRNA Protein Name
NM_007620.2 NP_031646.2 carbonyl reductase [NADPH] 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IDA
IDA: Inferred from direct assay
28878267 MGI
Biological Process GO Annotation Evidence References Source
involved in glucocorticoid metabolic process IDA
IDA: Inferred from direct assay
28878267 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

carbonyl reductase [NADPH] 1

  • 15-hydroxyprostaglandin dehydrogenase

  • 20-beta-hydroxysteroid dehydrogenase

  • Carbonyl reductase [NADPH] 1 (NADPH-dependent carbonyl reductase 1)

  • NADPH-dependent carbonyl reductase 1

  • alcohol dehydrogenase [NAD(P)+] CBR1

  • prostaglandin 9-ketoreductase

  • pr

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-155587 Hydroxy-PP Inhibitor 99.66% Unkown
HY-121710 MonoHER Inhibitor 97.02% Unkown
HY-157447 CBR1-IN-4 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cbr1 NCBI NCBI:873