Cbx3 - chromobox 3 Gene

Also Known as M32; HP1g

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12417

Summary

Enables transcription cis-regulatory region binding activity. Acts upstream of or within negative regulation of transcription, DNA-templated. Located in chromocenter; chromosome, centromeric region; and nuclear envelope. Is expressed in several structures, including central nervous system; embryo ectoderm; gonad; gut; and retina nuclear layer. Orthologous to human CBX3 (chromobox 3). [provided by Alliance of Genome Resources, Apr 2022]

Cbx3 Products (2)

mRNA Protein Name
NM_001355002.1 NP_001341931.1 chromobox protein homolog 3
NM_007624.4 NP_031650.3 chromobox protein homolog 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription factor binding IPI
IPI: Inferred from physical interaction
33795231 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
10330177 MGI
enables transcription cis-regulatory region binding IDA
IDA: Inferred from direct assay
24413057 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
10562550 MGI
Cellular Component GO Annotation Evidence References Source
located in chromatin IDA
IDA: Inferred from direct assay
16880268 MGI
located in chromocenter IDA
IDA: Inferred from direct assay
15322135 MGI
located in condensed chromosome, centromeric region IDA
IDA: Inferred from direct assay
11124534 MGI
located in heterochromatin IDA
IDA: Inferred from direct assay
10562550 MGI
located in nuclear envelope IDA
IDA: Inferred from direct assay
11101528 MGI
located in nucleus IDA
IDA: Inferred from direct assay
15469996 MGI
located in pericentric heterochromatin IDA
IDA: Inferred from direct assay
16287503 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

chromobox protein homolog 3

  • HP1 gamma

  • heterochromatin protein 1 gamma

  • heterochromatin protein 1 homolog gamma

  • modifier 2 protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-181089 CBX2-IN-1 Inhibitor / Unkown
HY-RS02010 CBX3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20257 Cbx3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26765 Cbx3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cbx3 NCBI NCBI:11335