Ccr9 - chemokine (C-C motif) receptor 9 Gene

Also Known as Cmkbr10; GPR-9-6; A130091K22Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12769

About Ccr9

Chromosome 9: 123,507,504-123,613,395 forward strand.GRCm39:CM001002.3

This gene has 6 transcripts (splice variants), 265 orthologues, 25 paralogues and is associated with 16 phenotypes. Restricted expression toward thymus adult (RPKM 118.6).

Summary

Enables C-C Chemokine Receptor activity. Acts upstream of or within CD8-positive, gamma-delta intraepithelial T cell differentiation and chemotaxis. Predicted to be located in cell surface. Predicted to be active in external side of plasma membrane. Is expressed in central nervous system; immune system; and retina. Orthologous to human CCR9 (C-C motif Chemokine Receptor 9). [provided by Alliance of Genome Resources, Apr 2022]

Ccr9 Products (2)

mRNA Protein Name
NM_001166625.1 NP_001160097.1 C-C chemokine receptor type 9
NM_009913.6 NP_034043.1 C-C chemokine receptor type 9

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables C-C chemokine receptor activity IDA
IDA: Inferred from direct assay
10623805 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
10623805 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within CD8-positive, gamma-delta intraepithelial T cell differentiation IMP
IMP: Inferred from mutant phenotype
25348153 MGI
acts upstream of or within chemotaxis IDA
IDA: Inferred from direct assay
10623805 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Ccr9 Protein Structure

7tm_GPCRs

7tm_GPCRs: cl28897 (48 - 327)

7tm_GPCRs

7tm_GPCRs: cd14964 (50 - 74)

7tm_GPCRs

7tm_GPCRs: cd14964 (83 - 104)

7tm_GPCRs

7tm_GPCRs: cd14964 (119 - 141)

7tm_GPCRs

7tm_GPCRs: cd14964 (166 - 182)

7tm_GPCRs

7tm_GPCRs: cd14964 (211 - 234)

7tm_GPCRs

7tm_GPCRs: cd14964 (252 - 274)

7tm_GPCRs

7tm_GPCRs: cd14964 (295 - 320)

  • 0
  • 100
  • 200
  • 300
  • 369 a.a.
Protein Preferred Names Protein Names

C-C chemokine receptor type 9

  • C-C CKR-9

  • CC-CKR-9

  • CCR-9

  • chemokine C-C receptor 10

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-15724 Vercirnon Antagonist 98.01% Phase 3

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-15724A Vercirnon sodium Antagonist 98.04% Unkown
HY-181288 CCR9 ligand-Linker Conjugate 1 Ligand / Unkown
HY-181287 PROTAC CCR9 Degrader 1 Degrader / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ccr9 NCBI NCBI:10803